An Open-Science Computational Model of Organelle Acidification to Integrate Putative Mechanisms of Synaptic Vesicle Acidification and Filling. [PDF]
Baraglia EC+4 more
europepmc +1 more source
TaPPR13, a PPR protein family gene in wheat is activated by TaBZR2 to enhance drought stress tolerance and photosynthetic capacity. It achieves this by interacting with TaAOR1 and TaSIG5 to improve antioxidant defense and regulate chloroplast gene expression. Abstract The wheat (Triticum aestivum) brassinazole‐resistant 2 (TaBZR2) gene is identified as
Ze‐Hao Hou+20 more
wiley +1 more source
A dynamic barrier: remodeling of the nuclear envelope during closed mitosis in malaria parasites. [PDF]
Absalon S.
europepmc +1 more source
A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy [PDF]
Allavena, Giulia+5 more
core +1 more source
Attachment of the adhesive holdfast organelle to the cellular stalk of Caulobacter crescentus
Christopher J. Ong+2 more
openalex +1 more source
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu+9 more
wiley +1 more source
Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska+18 more
wiley +1 more source
Nellie: automated organelle segmentation, tracking and hierarchical feature extraction in 2D/3D live-cell microscopy. [PDF]
Lefebvre AEYT+6 more
europepmc +1 more source
Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen+7 more
wiley +1 more source
Unraveling the mitochondrial genome of the medicinal Chinese motherwort (<i>Leonurus japonicus</i>, Lamiaceae): structural dynamics, organelle-to-nuclear gene transfer, and evolutionary implications. [PDF]
Bai X+10 more
europepmc +1 more source