Results 331 to 340 of about 463,135 (398)

STING COPII ER Export Trafficking and Signaling Primed by Phosphorylation Switches

open access: yesAdvanced Science, EarlyView.
This schematic outlines STING trafficking and signaling via coat protein II (COPII)‐mediated endoplasmic reticulum (ER) export. Following cyclic GMP‐AMP (cGAMP) stimulation, TANK‐binding kinase 1 (TBK1) activates on COPII vesicles, partially dissociating into the cytosol to phosphorylate ER‐localized STING, creating pSGME/pFS COPII‐sorting motifs ...
Yanan Nan   +10 more
wiley   +1 more source

Unraveling Tissue‐Specific Fatty Acid Biosynthesis and Inter‐Tissue Crosstalk in Mice through Stable‐Isotope Tracing Metabolomics

open access: yesAdvanced Science, EarlyView.
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing   +4 more
wiley   +1 more source

Organelle-oriented nanomedicines in tumor therapy: Targeting, escaping, or collaborating? [PDF]

open access: yesBioact Mater
Tan K   +9 more
europepmc   +1 more source

Organellar genome divergence and environmental stress induce transcriptional cytonuclear responses in wheat alloplasmic hybrids. [PDF]

open access: yesProc Natl Acad Sci U S A
Zhao Y   +18 more
europepmc   +1 more source

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