Results 51 to 60 of about 4,463,518 (291)
, 2009 This annual report describes a selection of contributions from researchers who, using organic chemistry tools and inspiration from biomolecular systems have developed new techniques, approaches and applications.
Tomas, Salvador
core +2 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Bioinspired organic chemistry [PDF]
[eng] This annual report reviews a selection of contributions from researchers in the field of organic chemistry broadly interpreted, which take inspiration from biomolecular systems.
Salvador Tomas, Lilia Milanesi
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Selective synthesis of meta-phenols from bio-benzoic acids via regulating the adsorption state
iScience, 2023 Summary: Phenols are important building blocks widely applied in many fields. The pronounced orientational effect of the phenolic hydroxyl group makes achieving selective synthesis of meta-phenols challenging.
Xinze Du +4 more
doaj +1 more source
Physical organic chemistry in the making [PDF]
, 1997 The discipline of physical organic chemistry will continue to occupy a central position in chemistry. The rapid increase in instrumentation and important theoretical developments allow the investigation of many problems of great complexity and challenge.
Engberts, J.B.F.N.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Organic chemistry as representation
Foundations of Chemistry, 2020 Electron redistribution is the cornerstone of our understanding of chemical reactivity. For the vast majority of organic reactions electrons are assumed to move in pairs providing explanatory mechanisms through the generation of intermediate structures.
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source