Results 191 to 200 of about 1,114,638 (302)
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
The high potential of methyl laurate as a recyclable competitor to conventional toxic solvents in [3 + 2] cycloaddition reactions. [PDF]
Yıldırım A, Göker M.
europepmc +1 more source
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna +6 more
wiley +1 more source
Engineering the Link: From Genome Interaction Maps to Functional Insight
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen +5 more
wiley +1 more source
A Different Perspective on the Solid Lubrication Performance of Black Phosphorus: Friend or Foe?
Researchers investigate black phosphorus (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli +5 more
wiley +1 more source
Determination of Retention Behavior and p<i>K</i> <sub>a</sub> Values of Some Phenothiazines with Green Chemistry Approach. [PDF]
Öztürk Z +2 more
europepmc +1 more source
Prikazi knjiga Spectroscopic Methods in Organic Chemistry / Manfred Hesse, Herbert Meier, Bernd Zeeh
Goran Baranović
openalex +1 more source

