Results 21 to 30 of about 103,835 (240)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Heterogeneous PMO@MXene nanocomposite: a robust and efficient nanocatalyst for two-component synthesis of highly substituted 2-(aryl)-1H-benzo[d]imidazole derivatives

Scientific Reports
In this work, a novel MXene-based nanocomposite, denoted as PMO@MXene, was synthesized for the first time and successfully applied as an efficient heterogeneous catalyst in the green synthesis of 2-(aryl)-1H-benzo[d]imidazole derivatives.
Safa Hanifi, Farhad Shirini, Bahram Ramezanzadeh, Hassan Tajik   +3 more
doaj   +1 more source

Influence of Ce(IV) ions amount on the electrochemical behavior of hybrid films in 0.1 mol L-1 NaCl solution

Eclética Química, 2019
In this work, the influence of ceric ions (Ce(SO4)2) addition to the hydrolysis solution on the corrosion protection afforded by organic-inorganic hybrid coating obtained from tetraethoxysilane (TEOS) and 3-methacryloxy-propyl-trimethoxysilane (MPTS) to ...
Fernando Santos da Silva, Hercílio Gomes de Melo, Assis Vicente Benedetti, Patrícia Hatsue Suegama   +3 more
doaj   +1 more source

4-Terminal Inorganic Perovskite/Organic Tandem Solar Cells Offer 22% Efficiency

Nano-Micro Letters, 2022
Highlights 4-Terminal inorganic perovskite/organic tandem solar cells were made by using semi-transparent inorganic perovskite solar cells and narrow-bandgap organic solar cells as the sub-cells, yielding a power conversion efficiency of 22.34%, which is
Ling Liu, Hanrui Xiao, Ke Jin, Zuo Xiao, Xiaoyan Du, Keyou Yan, Feng Hao, Qinye Bao, Chenyi Yi, Fangyang Liu, Wentao Wang, Chuantian Zuo, Liming Ding   +12 more
doaj   +1 more source

A Novel Multilayer Natural Coating for Fed-State Gastric Protection

Pharmaceutics, 2022
Several nutraceutical products require gastric protection against the hostile environment in the stomach. Currently marketed synthetic and semi-synthetic coatings suffer from major shortcomings such as poor gastric protection, slow-release response to pH
Rober Habashy, Mouhamad Khoder, Abdullah Isreb, Mohamed A. Alhnan   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Preparation and properties of Mg-Nd binary alloy MAO/SiO2@α-Fe2O3 organic composite coating

npj Materials Degradation
In order to make magnesium alloys better used in aviation, electronic information and other fields, it is necessary to improve their corrosion resistance and wave absorption properties.
Qiang Sun, Quantong Jiang, Siwei Wu, Chang Liu, Heng Tang, Hao Shi, Liying Song, Jizhou Duan, Baorong Hou   +8 more
doaj   +1 more source

Micro multi-nozzle jet coating of organic thin film for organic light-emitting diode lighting devices

Micro and Nano Systems Letters, 2021
Uniform deposition across large areas of an organic layer is one of the challenges for the industrial application of solution-based organic light‐emitting diode (OLED).
Kwon-Yong Shin, Mingyu Kang, Kwan Hyun Cho, Kyung-Tae Kang, Sang-Ho Lee   +4 more
doaj   +1 more source

Ultrasound−assisted sealing with different sealants for enhanced corrosion protection of HVOF−sprayed WC−Cr3C2−Ni/CNTs coating in 3.5 wt% NaCl solution

Alexandria Engineering Journal, 2023
High−velocity oxygen−fuel (HVOF) sprayed WC−Cr3C2−Ni/CNTs coatings were prepared on 430 stainless steel, and then were sealed with sol–gel aluminum phosphate (inorganic sealant) and silicone resin (organic sealant) by ultrasound−assisted sealing ...
Dongcheng Mei, Ziyu Wei, Kailin Wang, Zheng Wei, Sheng Hong   +4 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source