Results 111 to 120 of about 220,423 (353)

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Diversity-triggered deterministic bacterial assembly constrains community functions

Nature Communications, 2019
The role of microbial β-diversity in soil ecosystem function is not well-studied. Here, the authors use genetic data to show that microbial α-diversity levels may have impacts on stochastic/deterministic assembly processes and functions of soil ...
Weibing Xun, Wei Li, Wu Xiong, Yi Ren, Yunpeng Liu, Youzhi Miao, Zhihui Xu, Nan Zhang, Qirong Shen, Ruifu Zhang   +9 more
doaj   +1 more source

Optimizing crop loading of apples and pears - results 2004-2006 (foliar fertilizers, thinning) [PDF]

, 2008
Main topics of the research-project FuE 03OE088 of “Bundesprogramm Ökologischer Landbau” (30.04.2004-31.12.2006) were the testing of foliar fertilizers in organic apples and pears, optimizing lime sulphur for blossom thinning, looking for alternatives ...
Eis, B., Fieger-Metag, N., Pfeiffer, B., Zimmer, J.   +3 more
core  

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

Advanced Science, EarlyView.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia, Xiaoxuan Zhang, Bohang Zhang, Minhui Lu, Qing Cheng, Li Liu, Lifang Shi, Yiqiang Cui, Dingdong Chen, Laihua Li, Xuejiang Guo, Jingtao Guo, Jiahao Sha, Yuanjin Zhao, Yan Yuan   +14 more
wiley   +1 more source

Oilseed Meal as a Fertility Amendment in Sweet Corn [PDF]

, 2013
Many Northeast growers are integrating oilseed crops such as canola, soybeans, and sunflower into their operation, in hopes of on-farm fuel production, value-added products, and/or livestock feed.
Burke, Conner, Cummings, Erica, Darby, Heather, Harwood, Hannah Harwood, Monahan, Susan   +4 more
core   +1 more source

Role of Organic Manures and Inorganic Fertilizers in Maintaining Fertility Status of Paddy Soils [PDF]

, 1966
S VARADARAJAN, M GURUSWAMY, R KRISHNAMURTHI   +2 more
openalex   +1 more source

Cationic Peptoids for Systemic In Vivo Cartilage‐Targeting

Advanced Science, EarlyView.
Systemically‐dosed Cy5‐labeled cationic peptoid probe (NlysO)7 (yellow) binds to the cartilage's glycosaminoglycan content in vivo across the entire body of a neonatal mouse imaged by light sheet fluorescence microscopy, revealing fluorescence uptake in generic cartilage as well as the developing and ossifying bones.
Chaonan Zhang, Rongmao Qiu, Yongjie Huang, Yinghua Liu, Kui Huang, Suwen Zhao, Yang Li   +6 more
wiley   +1 more source

Oilseed Meal as a Fertility Amendment in Sweet Corn [PDF]

, 2014
Many Northeast growers are integrating oilseed crops such as canola, soybeans, and sunflower into their operation, in hopes of on-farm fuel production, value-added products, and/or livestock feed.
Cummings, Erica, Darby, Heather, Gupta, Abha, Monahan, Susan, Post, Julian, Ziegler, Sara   +5 more
core   +1 more source

Pectin Metabolism Influences Phloem Architecture and Flowering Time in Arabidopsis Thaliana

Advanced Science, EarlyView.
Cell wall remodeling mediated by changes in pectic homogalacturonan, including its methyl‐esterification status and degradation, shapes wall architecture. This study finds that pectin metabolism dynamically modulates wall properties and triggers auxin responses, which influence phloem morphogenesis and function, mediating the long‐distance transport of
Qing Zhang, Juan Du, Shuang Hao, Zhengmei Leng, Weiguo Liu, Chengjian Zhao, Yue Yu, Longquan Chen, Charles T. Anderson, Chaowen Xiao   +9 more
wiley   +1 more source

Organic fertilizer increases pumpkin production by improving soil fertility

Frontiers in Plant Science
Compared with long-term and continuous application of large amounts of chemical fertilizers, fertilizers with microbial organic nutrient sources can improve soil environment, increase soil fertility and increase crop yield. In view of the current low soil fertility and poor soil environment leading to low crop yield and instability in the arid regions ...
Fangfang Ren, Jinxia Zhang, Lin Ding, Rui Zhang, Fuqiang Li, Xuan Li, Tao Zhong, Meng Yin, Runheng Yang, Pengliang Tian, Liangliang Du, Kaiyuan Gan, Tian Yong, Qirun Li, Xingrong Liu   +14 more
openaire   +3 more sources