Results 111 to 120 of about 2,608,216 (300)

Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models

Advanced Science, EarlyView.
Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler, Tim Lange, Sophia‐Marie Bach, Soeren S. Lienkamp, Nicole Endlich   +4 more
wiley   +1 more source

Phosphorus availability influences disease-suppressive soil microbiome through plant-microbe interactions

Microbiome
Background Soil nutrient status and soil-borne diseases are pivotal factors impacting modern intensive agricultural production. The interplay among plants, soil microbiome, and nutrient regimes in agroecosystems is essential for developing effective ...
Yifan Cao, Zongzhuan Shen, Na Zhang, Xuhui Deng, Linda S. Thomashow, Ian Lidbury, Hongjun Liu, Rong Li, Qirong Shen, George A. Kowalchuk   +9 more
doaj   +1 more source

Transformation of Biomass Waste into Sustainable Organic Fertilizers

Sustainability, 2019
The management of solid waste presents a challenge for developing countries as thegeneration of waste is increasing at a rapid and alarming rate. Much awareness towards thesustainability and technological advances for solid waste management has been ...
K. Chew, Shir Reen Chia, Hong-Wei Yen, S. Nomanbhay, Y. Ho, P. Show   +5 more
semanticscholar   +1 more source

DTX3L Inhibits the EMT, Metastasis, and Stem‐Like Features of Gastric Cancer Through Promoting GSK‐3β Dependent SNAI1 Decay

Advanced Science, EarlyView.
This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen, Zhen Li, Jiajia Shen, Jingyu Lin, Xiaoli Zhao, Rui Zhang, Ying Han, Zhen Wang   +7 more
wiley   +1 more source

Mineral nitrogen input modulates the methane mitigation potential of biochar in rice systems: based on meta-analysis and field experiment demonstration

Biochar
The application of organic materials has a profound impact on CH₄ emissions from paddy fields. Biochar has been reported to mitigate CH₄ emissions, but this conclusion has recently been challenged and requires further investigation.
Weijie Huang, Xingyan Liu, Yu Deng, Daoyuan Zhao, Jun Yuan, Qirong Shen, Chao Xue   +6 more
doaj   +1 more source

TgSWO from Trichoderma guizhouense NJAU4742 promotes growth in cucumber plants by modifying the root morphology and the cell wall architecture

Microbial Cell Factories, 2019
Background Colonization of Trichoderma spp. is essential for exerting their beneficial functions on the plant. However, the interactions between Trichoderma spp. and plant roots are still not completely understood.
Xiaohui Meng, Youzhi Miao, Qiumei Liu, Lei Ma, Kai Guo, Dongyang Liu, Wei Ran, Qirong Shen   +7 more
doaj   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Organic fertilizer increases pumpkin production by improving soil fertility

Frontiers in Plant Science
Compared with long-term and continuous application of large amounts of chemical fertilizers, fertilizers with microbial organic nutrient sources can improve soil environment, increase soil fertility and increase crop yield. In view of the current low soil fertility and poor soil environment leading to low crop yield and instability in the arid regions ...
Fangfang Ren, Jinxia Zhang, Lin Ding, Rui Zhang, Fuqiang Li, Xuan Li, Tao Zhong, Meng Yin, Runheng Yang, Pengliang Tian, Liangliang Du, Kaiyuan Gan, Tian Yong, Qirun Li, Xingrong Liu   +14 more
openaire   +3 more sources

Effect of plant-derived microbial soil legacy in a grafting system—a turn for the better

Microbiome
Background Plant-soil feedback arises from microbial legacies left by plants in the soil. Grafting is a common technique used to prevent yield declines in monocultures.
Tingting Wang, Yang Ruan, Qicheng Xu, Qirong Shen, Ning Ling, Philippe Vandenkoornhuyse   +5 more
doaj   +1 more source