Results 71 to 80 of about 5,631,613 (358)

The content of bioactive compounds in rat experimental diets based on organic, low-input and conventional plant materials [PDF]

open access: yes, 2007
Rat feed based on raw plant materials was produced according to the nutritional recommendations for rat feeding trials. Rat feeds produced from crops grown under 4 different production systems were used: (a) organic, (b) conventional, (c) low input 1 ...
Bennett, Richard   +6 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Comparison of energy consumption and economic performance of organic and conventional soybean production — A case study from Jilin Province, China

open access: yesJournal of Integrative Agriculture, 2015
Modern agriculture heavily depends on energy consumption, especially fossil energy, but intensive energy input increases the production cost for producers and results in environmental pollution.
Li-wei ZHANG   +4 more
doaj   +1 more source

Determining consumer expectations and attitudes towards organic/lo-input food quality and safety. QLIF subproject 1: Consumer expectations and attitudes [PDF]

open access: yes, 2009
The objective of QLIF subproject 1 was to deliver in-depth analyses of consumer expectations, attitudes and buying behaviours, with respect to quality and safety of foods from organic and low-input production systems.
Oughton , E
core  

Dendritic Organization of Olfactory Inputs to Medial Amygdala Neurons [PDF]

open access: yesThe Journal of Neuroscience, 2015
The medial amygdala (MeA) is a central hub in the olfactory neural network. It receives vomeronasal information directly from the accessory olfactory bulb (AOB) and main olfactory information largely via odor-processing regions such as the olfactory cortical amygdala (CoA). How these inputs are processed by MeA neurons is poorly understood.
Keshavarzi, S   +4 more
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Direct payments coupled to labour force – socio-economic consequences to organic farming – [PDF]

open access: yes, 2002
Discussion Labour input on organic farms in Switzerland and Germany is on average 20% higher than on comparable conventional farms (Offermann and Nieberg 2000). Therefore, it is not surprising, that policy-makers expect positive impacts both on organic
Stolze, Matthias
core  

Characterization of Wastewater for Modelling of Activated Sludge Processes [PDF]

open access: yes, 1992
The fractionation of organic matter in the various parts which are used for mathematical modelling is discussed. The fractions include inert soluble, readily biodegradable, rapidly hydrolysable, slowly hydrolysable, biomass and inert suspended material ...
Henze, Mogens
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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