Results 71 to 80 of about 220,203 (266)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Rendimento de feijão e alterações no pH e na matéria orgânica do solo em função de doses de composto de resíduo de algodão Yield of bean plant and changes in pH and soil organic matter as a function of doses of compost cotton waste

open access: yesCiência Rural, 2009
O objetivo do presente trabalho foi avaliar o rendimento de feijão e as alterações no pH e na matéria orgânica do solo após a aplicação do composto de resíduo de algodão.
Sílvio Júnio Ramos   +3 more
doaj  

Formas de aplicação de cama-de-frango no crescimento e produção de capítulos florais de Calendula officinalis L. Chicken manure application forms on the growth and production of Calendula officinalis L. capitula

open access: yesRevista Brasileira de Plantas Medicinais, 2011
Este trabalho objetivou avaliar características fisiológicas, morfológicas e a produção de inflorescências em cultura de Calendula officinalis em função do fornecimento de cama-de-frango de corte semidecomposta.
H. Scalon Filho   +3 more
doaj   +1 more source

Cuisine in transition? Organic residue analysis of domestic containers from 9th-14th century Sicily. [PDF]

open access: yesR Soc Open Sci, 2023
Lundy J   +10 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Organic residue analysis reveals the function of bronze age metal daggers. [PDF]

open access: yesSci Rep, 2022
Caricola I   +14 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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