Results 61 to 70 of about 174,420 (237)
FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
wiley +1 more source
Biota and Biomolecules in Extreme Environments on Earth: Implications for Life Detection on Mars
Life, 2014 The three main requirements for life as we know it are the presence of organic compounds, liquid water, and free energy. Several groups of organic compounds (e.g., amino acids, nucleobases, lipids) occur in all life forms on Earth and are used as ...
Joost W. Aerts +3 more
doaj +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Advanced Science, 2020 Density functional theory calculations are combined with machine learning to investigate the coverage‐dependent charge transfer at the tetracyanoethylene/Cu(111) hybrid organic/inorganic interface.
Alexander T. Egger +7 more
doaj +1 more source
Long-range dispersion-inclusive machine learning potentials for structure search and optimization of hybrid organic-inorganic interfaces [PDF]
, 2022 Julia Westermayr +4 more
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Tracing early life on Mars: lessons from organics produced in high-altitude hotsprings of Ladakh
Progress in Earth and Planetary ScienceHotspring waters have traditionally been recognized for their therapeutic benefits. More recently, high-altitude hotsprings have received attention for astrobiological studies because they replicate several parameters of extreme conditions that once ...
Arif Husain Ansari +3 more
doaj +1 more source
A PROPAGAÇÃO DO ERRO DO pKa DA ÁGUA NOS LIVROS DE QUÍMICA ORGÂNICA [PDF]
Química NovaIn organic chemistry, the pKa is a property used to compare the acidity behavior for many substances, and to locate the position of equilibria in acid-base reactions and to provide information about structure and reactivity.
Leonardo Antonelli +2 more
doaj +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source