Results 121 to 130 of about 528,498 (289)
Development and validation of a HPLC method for the quantitative determination of active substance DIOL in dosage form [PDF]
, 2018 In this work was studied the substance DIOL, which has a therapeutic effect against the symptoms of Parkinson's disease ( in preclinical studies were conducted at the Institute of Organic Chemistry in Novosibirsk).
Пашковская, Э. А.
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Органичното вещество на почвата и неговото значение за растенията
Почвознание, агрохимия и екология, 2013 In the present work has been done an overview of the multiple role of the organic substance in the formation and maintenance of the soil fertility and the opportunities for replenishing the loss of organic carbon by organic fertilizers, especial place ...
ВЕЛИКА ЯНЕВА +3 more
doaj
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Стандартные образцы, 2017 The aim of this study was to develop and validate a gas chromatography methods of quantitative determination of residual organic solvents in substance of 5,7-bis-(meta-nitrophenylamino)-4,6-dinitrobenzofuroxan.
R. Sh. Markhabullina, L. M. Yusupova
doaj
Antibacterial marine bacterium deter luminous vibriosis in shrimp larvae [PDF]
, 2004 Inhibitory activity of a marine pigmented bacterium - Alteromonas sp. - isolated from Penaeus monodon Fabricius larva against pathogenic and environmental isolates of Vibrio harveyi was studied.
Abraham, T.J.
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Stability of salts and complexes of humic acids [PDF]
, 2009 Základem práce je studium vlivu přítomnosti kovů inkorporovaných do struktury huminových látek při tepelné zátěži za přítomnosti vzdušného kyslíku.
Nováčková, Kristýna
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source