Results 231 to 240 of about 124,566 (258)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Region-specific prevalence and associated factors of work-related musculoskeletal disorders among pilots of a commercial airline: a cross-sectional study. [PDF]

BMJ Open
Liu T, Zhang X, Pan J, Qi Y.
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Talent-Management in Nursing: Factors, Organisational Practices and Retention Indicators Among Portuguese Nurses-A Cross-Sectional Study. [PDF]

Nurs Rep
Quaresma T, Marques MC, Mota L.
europepmc   +1 more source

Contemporary Evidence on Interhospital Neonatal Transport as a Potentially Sepsis-Relevant Care Interval: A Scoping Review. [PDF]

Medicina (Kaunas)
Damian RO, Boldeanu L, Cucu MG, Siminel MA, Butoi MA, Belghiru VI, Puticiu MI, Tat RM, Oprita B, Assani MZ, Radulescu VM, Geormaneanu C, Boldeanu MV, Rotaru LT.   +13 more
europepmc   +1 more source

Co-assembly and self-sorting are not mutually exclusive in enantiomeric peptide systems. [PDF]

Chem Sci
Bianco S, Sonani RR, Marshall LJ, Loch AS, Doutch J, Egelman EH, Adams DJ.   +6 more
europepmc   +1 more source

Ketamine's impact on rumination-related brain dynamics: insights from a randomized controlled fMRI trial. [PDF]

Transl Psychiatry
Meiering MS, Weigner D, Gärtner M, Carstens L, Keicher C, Luippold G, Wunder A, Weigand A, Grimm S.   +8 more
europepmc   +1 more source

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Sustainability policies and practices in public sector organisations: The case of the Portuguese Central Public Administration

Journal of Cleaner Production, 2018
Ana Rita Domingues, Nuno Videira, Sandra Caeiro   +2 more
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