Results 41 to 50 of about 744,255 (260)
Midbrain Dopamine Neurons Defined by TrpV1 Modulate Psychomotor Behavior
Dopamine (DA) neurons of the ventral tegmental area (VTA) continue to gain attention as far more heterogeneous than previously realized. Within the medial aspect of the VTA, the unexpected presence of TrpV1 mRNA has been identified.
Gian Pietro Serra +4 more
doaj +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The Organization of the Organization [PDF]
Duane P. Schultz, Sydney Ellen Schultz
+5 more sources
تســويق الألعــاب الإلكترونيــة في مـصر عبـر مؤثــري اليوتيــوب وعلاقتــه بالصــورة الذهنيــة لــدى اللاعبيـن [PDF]
في الســنين الأولى لأللعــاب الورقيــة كان يلتــف النــاس حــول الشــخص الــذي يلعــب ملشــاهدته أثنــاء اللعــب وتشــجيعه، التــي زادت يف اآلونــةlive streaming، ولكــن مــع ظهــور منصــات البــث الخاصــة بألعــاب الفيديــوnewman، 2013) 1)، أصبــح ...
تهاني حسن حسين
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Physical health of the student as the main value of pedagogical process [PDF]
The features of physical health of students are considered. Factors which influence on the physical health of children of school age are rotined. Methodical experience of teachers of physical education is presented.
Deminskaya L.A.
doaj
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Anaesthetizing Pinctada radiata with MS 222
The effect of MS 222 for inducing anaesthesia in 60 P. radiata was studied under different concentration and various stimulating factors. Based on the results of mortality rate, induction time, duration of anaesthesia, recovery time, responses of the ...
F. Ehteshami; H. Binaei; Sh. Seyd moradi
doaj

