Results 91 to 100 of about 179,455,462 (284)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Empiric vs Preemptive Antifungal Strategy in High-Risk Neutropenic Patients on Fluconazole Prophylaxis: A Randomized Trial of the European Organization for Research and Treatment of Cancer. [PDF]

Clin Infect Dis, 2023
Maertens J, Lodewyck T, Donnelly JP, Chantepie S, Robin C, Blijlevens N, Turlure P, Selleslag D, Baron F, Aoun M, Heinz WJ, Bertz H, Ráčil Z, Vandercam B, Drgona L, Coiteux V, Llorente CC, Schaefer-Prokop C, Paesmans M, Ameye L, Meert L, Cheung KJ, Hepler DA, Loeffler J, Barnes R, Marchetti O, Verweij P, Lamoth F, Bochud PY, Schwarzinger M, Cordonnier C, Infectious Diseases Group and the Acute Leukemia Group of the European Organization for Research and Treatment of Cancer.   +31 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Methodical Basics of Future Philologists’ Research Culture Formation

Journal of Danubian Studies and Research, 2013
the article discloses the notion of “research culture of future philologists” and gives general characteristics of organizational forms of educational process for the most effective development of the phenomenon under consideration and outlines the ...
Marina Trufkina
doaj  

J itegemee (rely on yourself): a multi-phase process of co-creating a personal savings intervention with female sex workers in western Kenya to reduce their HIV risk

BMC Public Health
Background HIV prevalence among female sex workers (FSW) is significantly higher than among women in the general population. Studies have shown that FSW engage in unprotected sex which provides higher compensation when they face emergency situations.
Kawango Agot, Jacob Onyango, Marylyn Ochillo, Timothy Omondi Okello, Shantana Carol, Tobias Odwar, Jane Moraa, Sophie Otticha, Redempter Odeny, Nicky Okeyo, Linet Ochieng, Gerald Ochieng, Ivy Wango, Alloys Koloo, Jacinta Badia, Carol S. Camlin, Bernard Ayieko, Sue Napierala, Harsha Thirumurthy   +18 more
doaj   +1 more source

Latest FLUKA developments

EPJ Nuclear Sciences & Technologies
The FLUKA Monte Carlo code has recently undergone significant enhancements, driven by needs from its user community. Key improvements are discussed, such as a new point-wise treatment for the interactions of low-energy neutrons, the incorporation of a ...
Hugo Gabrielle, Ahdida Claudia, Bozzato Davide, Calzolari Daniele, Cerutti Francesco, Ciccotelli Alessia, Cimmino Anna, Devienne Arnaud, Donadon Servelle Andre, Dyrcz Patrycja K., Salvatore Esposito Luigi, Formento Alice, Froeschl Robert, García Alía Ruben, Gilardoni Simone, Gomes Andrea, Horváth Dávid, Humann Barbara, Infantino Angelo, Lechner Anton, Lefebvre Benoit, Lerner Giuseppe, Lorenzon Tommaso, Lucsanyi David, Magistris Matteo, Marin Stefano, Mazzola Giuseppe, Niang Samuel, Nowak Elzbieta, Ogallar Ruiz Francisco, Potoine Jean-Baptiste, Pozzi Fabio, Prelipcean Daniel, Rodin Volodymyr, Roesler Stefan, Sabaté Gilarte Marta, Sacristan Barbero Mario, Salvat Pujol Francesc, Schoofs Philippe, Şerban Alexandra-Gabriela, Sharankov Ivan, Theis Chris, Tisi Marco, Tsinganis Andrea, Versaci Roberto, Vlachoudis Vasilis, Waets Andreas, Widorski Markus, Zymak Illia   +48 more
doaj   +1 more source

Transfusion use and effect on progression-free, overall survival, and quality of life in upfront treatment of advanced epithelial ovarian cancer: evaluation of the European Organization for Research and Treatment EORTC-55971 Cohort. [PDF]

Int J Gynecol Cancer, 2023
Prescott LS, Vergote I, Sun CC, Bodurka DC, Coleman RL.   +4 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Future orientation of research.

, 1977
42142

core  

Consideration of Application for Subvention from Pan-African Women's Organization

, 1979
Council of Ministers Thirty-Second Ordinary Session Nairobi, Kenya- 23 February-3 March 1979This report considers the application for Subvention from the Pan-African Women's Organization to the Organization of African Unity as well as the report on the ...
Organization of African Unity
core   +1 more source