Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Reimagining Healthcare Management and Leadership in Somalia: A Commentary Proposing an Eight-Pillar Conceptual Framework for a Mixed Public-Private Health System. [PDF]
Osman AI.
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Preparing for Ebola: Strengthening Nursing Readiness in the United States. [PDF]
Lindsay B.
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
ACTIVE problem solving: An action-oriented method for transforming Complex or Chaotic problems into verified reusable solutions. [PDF]
Vermaak R, Roopa M, Grobbelaar S.
europepmc +1 more source
Improving Medication Management in Indonesian Aged Care Homes: Research Priority Setting With Stakeholders. [PDF]
Sari YM +13 more
europepmc +1 more source
BIM-Supported green building adoption in the construction industry. [PDF]
Alrasheed KA +5 more
europepmc +1 more source

