Results 91 to 100 of about 1,584,945 (320)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Exploring The Way The Lecturer Develop Reading Material at State Islamic Institute of Lhokseumawe

open access: yesEnglish Education Journal: Jurnal Pengembangan Pendidikan dan Pengembangan Pengajaran Bahasa, 2019
Reading material is one of the required subject stated in the curriculum at English Department of State Islamic Institute of  Lhokseumawe which is designed by the lecturer for her own class.
Cut Barlianti Taufiqiani   +2 more
doaj  

A Neural Model of How The Brain Represents and Compares Numbers [PDF]

open access: yes, 1999
Many psychophysical experiments have shown that the representation of numbers and numerical quantities in humans and animals is related to number magnitude.
Grossberg, Stephen, Repin, Dmitry
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Replication strategies and design solutions for a creative and collaborative organization

open access: yesProjetica, 2017
Social innovation has emerged from creative and collaborative organizations. It is assumed that such initiatives can be replicated and/or improved through of design solutions.
Debora Barauna   +2 more
doaj   +1 more source

TEACHING ACADEMIC WRITING BASED ON NEED ANALYSIS FOR INDONESIAN EFL LEARNERS AT UNIVERSITY [PDF]

open access: yes, 2016
there are four skills in English teaching and learning, they are listening, speaking, reading, and writing. Listening and reading are categorized as receptive skills, while speaking and writing are as productive skills.
Prastyo, Hari
core  

The Message is the Medium: Electronically Helping Writing Tutors Help Electronically [PDF]

open access: yes, 2013
The history of online writing centers is a history of doubt. I experienced those reservations in 2009, when, in addition to traditional face-to-face peer tutoring, I launched my own online peer tutoring program and began training undergraduates to ...
Kavadlo, Jesse
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Researcher self-care in organizational ethnography: lessons from overcoming compassion fatigue [PDF]

open access: yes, 2018
Purpose – The purpose of this paper is to offer practical researcher self-care strategies to prepare for and manage the emotions involved in doing organizational ethnographic research. Institutional ethics policies or research training programmes may not
Vincett, Joanne
core   +1 more source

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