Results 61 to 70 of about 1,241,052 (293)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Organizational communication process

open access: yesEkonomski Vjesnik, 2012
Managers spend majority of their time communicating in several forms: meeting, face-to –face dis- cussion, letters, emails etc. Also more and more employees realize that communication is a very im- portant part of their work because a lot of their work
Kenan Spaho
doaj  

The role of network administrative organizations in the development of social capital in inter-organizational food networks [PDF]

open access: yes, 2012
This paper is concerned with the role of network administrative organizations (NAOs) in the development of social capital in inter‐organizational networks aiming at supporting their members to innovate in the food sector through interacting with one ...
Gellynck, Xavier   +2 more
core   +5 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Downsizing: Some Aspects ofCommunication and Social Impact [PDF]

open access: yes
This study, being essentially empirical in nature, is based on primary data relating to Indian organizations. The primary data has been collected through a sample survey based on a questionnaire focusing on the following aspects of organizational ...
Dholakia Jigisha, Monippally, M. M.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Role of Organizational Communication in Enhancing Organizational Efficiency

open access: yesJournal of Social Sciences and Humanities
Effective organizational communication is a fundamental pillar of any organization's success and plays a vital role in ensuring coordination, increasing motivation, and improving the performance of the organization's personnel.
Mohammad Zahid Bahand
doaj   +1 more source

Organizational Communication in Implementing School Committee Role in South Tangerang City [PDF]

open access: yes, 2017
This research aims to explore the role of communication practices of organizations in supporting the implementation of the four roles of School Committee as an advisory body, a controller, a supporter and a intermediator in an education unit.
Ayuna, N. E. (Novianty)   +3 more
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

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