Results 71 to 80 of about 18,869,475 (349)

CASE Tools as Organizational Change: Investigating Incremental and Radical Changes in Systems Development

open access: yesMIS Q., 1993
This paper presents the findings of an empirical study into two organizations' experiences with the adoption and use of CASE tools over time. Using a grounded theory research approach, the study characterizes the organizations' experiences in terms of ...
W. Orlikowski
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Inter-American Development Bank Quarterly Business Review: First Quarter 2016

open access: yes, 2016
The 2016 first quarter edition of the Quarterly Business Review (QBR) provides management with a status of the Bank\u27s performance. The QBR reports on outputs, lending program priorities and organizational indicators on a quarterly basis to allow ...
Inter-American Development Bank
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The concept and application of simplified robotic models [PDF]

open access: yesSerbian Journal of Electrical Engineering, 2019
The use of robotic models with the main functionalities of real objects together with the implementation of innovative technologies, augmented reality (AR) in this case, is the focus of the paper.
Dodevska Zorica A.   +3 more
doaj   +1 more source

Inter-American Development Bank Quarterly Business Review: Second Quarter 2014

open access: yes, 2014
The 2014 second quarter edition of the Quarterly Business Review (QBR) provides management with a status of the Bank\u27s performance. The QBR reports on outputs, lending program priorities and organizational indicators on a quarterly basis to allow ...
Inter-American Development Bank
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Navigating AI Integration in Career and Technical Education: Diffusion Challenges, Opportunities, and Decisions

open access: yesEducation Sciences
This review paper explores the integration of artificial intelligence (AI) in career and technical education (CTE). CTE is an educational domain often overlooked in discussions about teaching and learning and notably omitted in the extant literature ...
Jeffrey C. Sun, Taylor L. Pratt
doaj   +1 more source

Inter-American Development Bank Quarterly Business Review: Second Quarter 2015

open access: yes, 2015
The 2015 second quarter edition of the Quarterly Business Review (QBR) provides management with a status of the Bank\u27s performance. The QBR reports on outputs, lending program priorities and organizational indicators on a quarterly basis to allow ...
Inter-American Development Bank
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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