Results 41 to 50 of about 10,123 (262)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The evolution of organizational safety culture: A theoretical study

open access: yesChemical Engineering Transactions, 2019
The study of organizational safety culture can be divided into the static study and the dynamic study. Many of its static studies have been carried out which focused on its definition, structure, construction, assessment and its impact on organizational ...
Bing Wang, Chao Wu
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Relationships Among Organizational-Level Maturities in Artificial Intelligence, Cybersecurity, and Digital Transformation: A Survey-Based Analysis

open access: yesIEEE Access
The rapid development of digital technology across industries has highlighted the growing need for enhanced competencies in Artificial Intelligence (AI), Cyber security (CS), and Digital Transformation (DT).
Burak Kubilay, Baris Celiktas
doaj   +1 more source

How do organizational capabilities mature? maturity level characteristics for organizational capabilities

open access: yesSoftware and Systems Modeling
Abstract In a dynamic business environment, organizations must continuously evolve to sustain a competitive edge by developing new capabilities while also enhancing the existing ones. Maturity models have become a useful management tool for enhancing organizational capabilities, offering a structured framework to assess and improve ...
Ginger Korsten   +4 more
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

PROJECT MANAGEMENT MATURITY MODELS. A REVIEW OF CURRENT CRITICISM AND OPPORTUNIEIS

open access: yesAnnals of the University of Oradea: Economic Science
Project management maturity models (PMMMs) have evolved significantly over the years, eliciting both enthusiasm and critique from professionals in the field.
Radu-Adrian MARINCEAN
doaj   +1 more source

The effect of strategic leadership and innovative organizational climate on employees' voice with the mediating role of work ethic maturity [PDF]

open access: yesمدیریت و چشم انداز آموزش
The present study was conducted with the aim of providing a structural model of the impact of strategic leadership and innovative organizational climate on the voice of employees with the mediating role of work ethic maturity in vocational universities ...
Jafar Beikzad, Maryam Razmjou
doaj   +1 more source

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