Results 61 to 70 of about 127,352 (253)

The Effect of Organizational Structure on the Entrepreneurial Spirit of the Staff Working in Vice-Chancellor for Treatment of Ahvaz Jundishapur University of Medical Sciences

open access: yesRāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat, 2019
Background: In modern organizations, establishment and utilization of the entrepreneurial thinking are inevitable. Entrepreneurial thinking is considered as the insight and ability of the founders as well as the cause of the organizations' birth and ...
Ozhan Karimi   +2 more
doaj  

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Information Analytics in the Organizational Structure of Libraries of Top-Rated Universities in Ukraine

open access: yesUniversity Library at a New Stage of Social Communications Development, 2019
Objective. To study of the organizational information and analytical structures of libraries of top-rated universities in Ukraine, in particular, of 4 domestic universities that entered the World University Rankings 2019.  Methods.
O. M. Kobelev
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

LA CULTURA COMO MECANISMO DE GOBIERNO Y CONTROL EN LAS ORGANIZACIONES COOPERATIVAS/THE CULTURE LIKE MECHANISM OF GOVERNMENT AND CONTROL IN THE COOPERATIVE ORGANIZATIONS [PDF]

open access: yesRevista de Estudios Cooperativos, 2008
El presente trabajo identifica la cultura como una de las piezas básicas del comportamiento organizativo en una cooperativa pues integra el conjunto de normas sociales, valores, principios y conductas comunes a los individuos que conforman la ...
Mª Jesús HERNÁNDEZ ÓRTIZ   +2 more
doaj  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Procesual and Structural Organisational Features of Small Business [PDF]

open access: yesRevista de Management Comparat International, 2009
The study is aimed to highlight the particularities of the procesual organization and structural organization in the SMEs, starting from the main variables that have influence on them.
Ovidiu NICOLESCU, Ciprian NICOLESCU
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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