Results 161 to 170 of about 7,899,703 (296)

Practice assistants´ perceived mental workload: A cross-sectional study with 550 German participants addressing work content, stressors, resources, and organizational structure. [PDF]

PLoS One, 2020
Hoffmann J, Kersting C, Weltermann B.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Emergency medical service organizational structure and prehospital outcomes after out-of-hospital cardiac arrest in China: Insights from the BASIC-OHCA. [PDF]

Resusc Plus
Xie X, Peng Y, Gao Q, Li B, Jiang G, Wang N, Song R, Ma J, Cheng K, Zhang J, Wang C, Bian Y, Liu R, Pan C, Shang R, Hock Ong ME, Zheng W, Xu F.   +17 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Change in Organizational Structure Influences Perceived Leadership in a Dutch Radiotherapy Center. [PDF]

J Healthc Leadersh
Swart RR, Jacobs MJG, Van Merode F, Boersma LJ.   +3 more
europepmc   +1 more source

Applying Organizational Routines in understanding organizational change [PDF]

Organizational routines are considered basic components of organizational behavior and repositories of Organizational capabilities (Nelson and Winter, 1982). They do, therefore, hold one of the keys to understanding organizational change.
Markus Becker, Richard Nelson, Nathalie Lazaric, Sidney G. Winter   +3 more
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Changing the Organizational Structure and Enhancing Nurse-Staffing Levels Based on Patient Acuity in a Tertiary Referral Hospital. [PDF]

J Nurs Manag
Martínez-Muñoz M, Barba-Flores MA, Andrés Escobedo D, Batuecas-Duelt IJ, López-Branchadell S, Rubio-Garrido P, Osorio D, Zuriguel-Pérez E.   +7 more
europepmc   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Study on Electrical Characteristics and ECG Signal Acquisition Performance of Fabric Electrodes Based on Organizational Structure and Wearing Pressure. [PDF]

Micromachines (Basel)
Wang M, Zhou J, Zhang G.
europepmc   +1 more source