Results 101 to 110 of about 127,352 (253)

Library as a social cluster information support

open access: yesБиблиосфера, 2015
The article analyzes modern library capability as a social cluster information support. A social cluster information support is offered to be considered not only as technological processes, but also as a process of intellectual resources exchange, that ...
O. Yu. Murashko
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Method for automatic reorganization of the structure of multi-agent systems, based on the application of the simulated hardening algorithm

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки
Background. The organizational structure of a multi-agent system includes many roles of agents, their horizontal and vertical connections, components that control their behavior, as well as rules for their functioning.
Yu.V. Dubenko   +2 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

INDUSTRIAL ENTERPRISE MANAGEMENT SYSTEM QUALITY ASSESMENT

open access: yesМодернизация, инновация, развитие, 2016
Management systems of small-scale enterprises in Moscow region are of centralized linear type. Misunderstanding of the need for qualitymanagement operational processes is observed in such business structures.
S. V. Pankov
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

METHODICAL APPROACHES TO FORMING INNOVATIVE PROJECT AND ENTERPRISE MANAGEMENT ORGANIZATIONAL STRUCTURES

open access: yesМодернизация, инновация, развитие, 2016
The following principles are discussed as methodical bases of the choice of innovative project and enterprise management organizational structures: hierarchism, bureaucratization, adhocratie, tent organization, lean business engineering, rational ...
A. O. Baklanov   +3 more
doaj  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

BANK TRANSFER LIQUIDITY

open access: yesМодернизация, инновация, развитие, 2016
A speculation on the transfer of bank liquidity is put forward. Substantiation of the relevance and necessity to study the topic is provided for. Materials on up-to-date bank liquidity management approaches are presented, a three-tier structure of the ...
S. M. Karasyova
doaj  

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