Results 131 to 140 of about 8,138,056 (213)
, 2018 Similar to other financial organizations, life insurance institutions are dealing with changes caused by the aging of the American population and technological advances. In addition, they are dealing with changes in the cultural and economic environment.
Krishnan, Rajesh R.
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FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
RESEARCH APPROACHES TO THE ANALYSIS OF «MAN-PRODUCTION» RELATIONS
Russian Journal of Economics and Law, 2014 Objective: to identify and describe research approaches, used in the analysis of the relationship between humans and production. Methods: in this work, we have applied the methods of grouping, describing and historical and logical method.
L. A. Otstavnova
doaj
The MNC as a Knowledge Structure The Roles of Knowledge Sources and Organizational Instruments in MNC Knowledge Management [PDF]
Recent research on the differentiated MNC has concerned knowledge flows between MNC units. While linking up with this literature, we extend in two directions.
Nicolai J. Foss, Torben Pedersen
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Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Architecture of organizational structure in selected company
, 2009 The theoretical part is intent on organization, organizational structure and types of organizational structure. The practical part contains analysis of organization structure of the pharmaceutical wholesale trade.
JAREŠOVÁ, Jana
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Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Organizational Structures in Industrial Organizations
This paper analyses Organization Development, thinking of structure as important factor for company competitiveness. In this paper author analyzes the change process as core point in building company structure, the level of responsiveness of ...
Šatrevičs, Vladimirs
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