Results 71 to 80 of about 127,426 (254)

Procesual and Structural Organisational Features of Small Business [PDF]

open access: yesRevista de Management Comparat International, 2009
The study is aimed to highlight the particularities of the procesual organization and structural organization in the SMEs, starting from the main variables that have influence on them.
Ovidiu NICOLESCU, Ciprian NICOLESCU
doaj  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Role of machine and organizational structure in science. [PDF]

open access: yesPLoS One, 2022
Thu MK, Beppu S, Yarime M, Shibayama S.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Harmonizing Growth: Leadership Competencies’ Mediation in SMEs’ Organizational Culture and Structure Through Schein’s Model

open access: yesSAGE Open
Based on Edgar Schein’s Organizational culture and leadership theory, this quantitative cross-sectional study examined how leadership competencies mediate the relationship between organizational culture and structure.
Hayford Asare Obeng   +3 more
doaj   +1 more source

Adaptive Complexity: Examining Texas Public Postsecondary Institutions’ Provision of Student Basic Needs Programs

open access: yesTrends in Higher Education
This study reveals that the likelihood and diversity of postsecondary institutions providing basic needs programs are significantly influenced by institutional factors such as the institutions’ organization and size.
Lisa K. Zottarelli   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Mapping Current Organizational Structure and Improvement Points of Breast Cancer Multidisciplinary Team Meetings - An Interview Study. [PDF]

open access: yesJ Multidiscip Healthc, 2022
Kočo L   +6 more
europepmc   +1 more source

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