Results 151 to 160 of about 5,450,086 (313)
Information management in healthcare organizations [PDF]
The health care industry is currently experiencing numerous fundamental changes. Healthcare organizations (HCOs) are increasingly challenged to look at their operations and find new opportunities to reorganize their processes, in order to improve the ...
COLESCA Sofia Elena, DOBRICA Liliana
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Coalition of Italo-American Organizations Speech: Draft [PDF]
, 1984 Draft of a speech delivered at the first Annual Dinner of the Coalition of Italo-American Organizations, New York, NY, September 14, 1984. Includes handwritten notes.https://ir.lawnet.fordham.edu/vice_presidential_campaign_speeches_1984/1097/thumbnail ...
Ferraro, Geraldine
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Capacity Building and Resilience [PDF]
, 2014 This report from Arts Midwest, investigates how small and mid-sized arts organizations learn, adapt, and grow. Examining the experiences of eight organizations participating in this leadership and strategy development program, this report identifies four
M. Christine Dwyer, Sarah Lutman
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
IEEE AEROSPACE & ELECTRONIC SYSTEMS SOCIETY ORGANIZATION 2021 [PDF]
, 2021 Walter Downing +70 more
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source