Results 51 to 60 of about 687,951 (314)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Has the Reform of the Japanese Healthcare Provision System Improved the Value in Healthcare? A Cost-Consequence Analysis of Organized Care for Hip Fracture Patients. [PDF]
PLoS ONE, 2015 To assess the value of organized care by comparing the clinical outcomes and healthcare expenditure between the conventional Japanese "integrated care across specialties within one hospital" mode of providing healthcare and the prospective approach of ...
Haruhisa Fukuda +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Community ScienceThe goal of this paper is to demonstrate the value of incorporating evaluation into the process of co‐produced research in pursuit of climate services. We aim to spur interest in and expand the use of evaluation throughout the climate change and climate ...
E. Figus +7 more
doaj +1 more source
The changing patterns of group politics in Britain [PDF]
, 2008 Two interpretations of ways in which group politics in Britain have presented challenges to democracy are reviewed: neo-corporatism or pluralistic stagnation and the rise of single issue interest groups.
Grant, Wyn, Wyn Grant
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
COMBATING ORGANIZED CRIME IN UKRAINE: CURRENT PROBLEMS AND POSSIBLE SOLUTIONS
Стратегічна панорамаThis article presents the findings of a state-of-the-art analysis of Ukrainian legislation in the field of combating organized crime. The authors focus on specific features of meeting Ukraine’s obligations under the United Nations Convention against ...
Олександр Володимирович Шамара +1 more
doaj +1 more source
Детские инфекции (Москва), 2016 The authors estimated epidemiological effectiveness of the program for prophylaxis of influenza and ARVI «Antigripp» for children of 7—12 years old. Children received Arbidol (capsules of 100 mg 2 times a week for 3 weeks) and Complivit activ.
I. B. Yakovlev +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Journal of Asian Architecture and Building Engineering, 2022 This paper presents an analysis of an Urban Hanok (improved Korean traditional housing), created in the process of Seoul’s urbanization since the 1930s as anew housing type from traditional Hanoks, using aspace syntax methodology to uncover the ...
Jungmin Kim, Dongyun Kwak
doaj +1 more source