Results 41 to 50 of about 212,551 (260)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Labor Unions and the Great Recession

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences, 2017
This article examines the impact of the Great Recession on the U.S. labor movement. After reviewing the classic industrial relations literature on the relationship between unionization rates and business cycles, we analyze historical union density trends.
Ruth Milkman, Stephanie Luce
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

THE ROLE OF THE PUBLIC ADMINISTRATOR - MAIN TENDENCIES IN MANAGEMENT AND LEADERSHIP SKILLS OF PUBLIC ADMINISTRATOR IN ROMANIA [PDF]

open access: yesChallenges of the Knowledge Society, 2016
The public administrator (city manager) has to be a professional in mastering the science of planning, organizing, directing, coordinating, reporting, and budgeting.
Constantin BRĂGARU
doaj  

Symbolic Interaction of Director of Photography in Film Production Organizing at Camera Department

open access: yesKomunikator, 2019
Film production is a collaborative work process that involves many workers. Proper management is needed to achieve effective and efficient production results. Organizing is the second function of management work.
Citra Dewi Utami, Budi Dwi Arifianto
doaj   +1 more source

How One Direction prepared young women for the revolution

open access: yesTransformative Works and Cultures, 2020
The One Direction fandom demonstrates the ways in which the online networks common to fandom can play a critical role in the informal training and education of young women.
Rachel O'Leary Carmona
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

THE REGIONAL ECONOMIC PROGRESS AND THE NATURAL CHARACTERISTICS OF THE TERRITORIES

open access: yesJournal of Bio-Based Marketing, 2023
This article is dedicated to the importance of the natural complex for the achievement of regional economic growth in individual territories. The presentation presents the topicality of the problem based on regional development and natural-geographical ...
Mihaela Georgieva1
doaj  

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