Results 71 to 80 of about 1,575,012 (307)

Promise Arizona: Building Immigrant Political Power [PDF]

open access: yes, 2013
This case study investigates the history and accomplishments of one organization that is making considerable strides in advancing the values and political interests of the Latino community.
Margaret A. Post
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

THE REGIONAL ECONOMIC PROGRESS AND THE NATURAL CHARACTERISTICS OF THE TERRITORIES

open access: yesJournal of Bio-Based Marketing, 2023
This article is dedicated to the importance of the natural complex for the achievement of regional economic growth in individual territories. The presentation presents the topicality of the problem based on regional development and natural-geographical ...
Mihaela Georgieva1
doaj  

Creating a Culture of Organizing: ACTWU\u27s Education for Empowerment [PDF]

open access: yes, 1991
[Excerpt] Providing rank-and-file members opportunities to participate and learn from their own experiences in organizing other workers is not only a very powerful educational tool.
La Luz, Jose
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Condensing of self-organizing groups [PDF]

open access: yes, 2010
Condensing phenomena for systems biology, ecology and sociology present in real life different complex behaviors. Based on local interaction between agents, we present another result of the Energy-based model presented by [20].
Zahri, Mostafa
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Fear, Conflict, and Union Organizing [PDF]

open access: yes, 1998
[Excerpt] Workers\u27 fears—of job loss, of strikes, of management retaliation—are well-documented obstacles to successful union organizing. Exploiting these fears is at the heart of employers\u27 union-avoidance strategies.
Hurd, Richard W
core   +1 more source

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