CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G +13 more
core
Pneumopathie médicamenteuse sous sirolimus : interaction avec l’atorvastatine ? [PDF]
Introduction Sirolimus is an immunosupressant used in renal transplantation because of its lack of nephrotoxicity. We report four cases of pneumonitis due to sirolimus, possibly revealing an interaction with atorvastatin.
A. Foulet-Rogé +6 more
core +4 more sources
A 40‐year‐old man had considered himself to be robust, with the exception of an earlier diagnosis of hepatitis C. He underwent a wedge resection of the lung, at the left upper lobe (LUL), mimicking an anterior mediastinal tumor. A pathology report showed
Sen‐Ei Shai +3 more
doaj +1 more source
Nanozyme Microrobots: Programmable Spatiotemporal Catalysis for Targeted Therapy and Diagnostics
This review presents nanozyme microrobots as emerging catalytic systems that integrate mobility, external actuation, and adaptive reactivity to achieve precise biochemical functions. By examining mobility‐regulated catalysis, spatial targeting, integrated designs, and translational demonstrations, the article highlights how nanozyme robotics enables ...
Hong Huy Tran +5 more
wiley +1 more source
Organizing for Higher Performance: Case Studies of Organized Delivery Systems [PDF]
Offers lessons learned from healthcare delivery systems promoting the attributes of an ideal model as defined by the Fund: information continuity, care coordination and transitions, system accountability, teamwork, continuous innovation, and easy ...
Douglas McCarthy, Kimberly Mueller
core
TIV vaccination modulates host responses to influenza virus infection that correlate with protection against bacterial superinfection [PDF]
Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or the
Choi, Angela +4 more
core +2 more sources
Case of Severe Treatment-Resistant Cryptogenic Organizing Pneumonia
Cryptogenic organizing pneumonia is a rare interstitial lung disease with different onset of symptoms, which responds rapidly to glucocorticoid treatment.
Domas Grigoravičius +4 more
doaj +1 more source
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara +14 more
wiley +1 more source
Comparing the effectiveness of small-particle versus large-particle inhaled corticosteroid in COPD [PDF]
Dirkje S Postma,1 Nicolas Roche,2 Gene Colice,3 Elliot Israel,4 Richard J Martin,5 Willem MC van Aalderen,6 Jonathan Grigg,7 Anne Burden,8 Elizabeth V Hillyer,8 Julie von Ziegenweidt,8 Gokul Gopalan,9 David Price8,10 1University of Groningen, Department ...
Burden, A +11 more
core +6 more sources

