Results 61 to 70 of about 49,961 (223)

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation

BMEMat, EarlyView.
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh, Varsha Sagar, Amal George Kurian, Shreyas Kumar Jain, Hye Sung Kim, Hae‐Won Kim   +5 more
wiley   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Drosophila male genitalia rotation depends on permissive remodeling of the posterior abdomen

Developmental Dynamics, EarlyView.
Abstract Background One of the most characteristic morphogenetic processes in Drosophila is the 360° rotation of the male pupal genital disc. This movement is driven by the myosin Myo1D, whose expression in the genital disc is controlled by the Hox gene Abdominal‐B (Abd‐B).
Nuria Prieto, David Foronda, Paloma Martín, Eléanor Simon, Marcus Bischoff, Stéphane Noselli, Ernesto Sánchez‐Herrero   +6 more
wiley   +1 more source

The womb as the cradle of longevity: Perinatal origins of biological aging

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The perinatal period is increasingly recognized as an important determinant of biological aging trajectories and disease susceptibility across the lifespan. This narrative review synthesizes current evidence linking intrauterine exposures to adult health outcomes across three biological dimensions: fetal programming, maternal influences, and ...
Sevim Ozge Ozdemir, Ebru Davutoglu
wiley   +1 more source

miR172-AP2 Controls Age-Dependent Regeneration Competence in Populus. [PDF]

Plant Biotechnol J
ABSTRACT Plants maintain remarkable regenerative potential, yet this capacity declines with developmental age, limiting clonal propagation and biotechnological applications. Here, we show that the miR172‐AP2 module serves as a central determinant of regeneration competence in Populus.
Lyu K, Azeez A, Busov V.
europepmc   +2 more sources

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

Regeneración de Sedum praealtum A.DC (siempreviva) vía organogénesis

Nova Scientia, 2016
La siempreviva (Sedum praealtum A.DC) pertenece a la familia Crassulaceae, desde hace  mucho tiempo ha sido utilizada en la etnobotánica mexicana como un agente anti-inflamatorio y analgésico, en el tratamiento de dolor de dientes, amigdalitis, para ...
Domingo Ruvalcaba Ruiz
doaj   +3 more sources

Organogénesis indirecta a partir de segmentos de hojas cotiledonares e hipocótilo de fresa (Fragaria ananassa Duchesne 1766), Piura [PDF]

, 2022
La fresa (Fragaria ananassa Duchesne 1766) es un cultivo de importancia global y nacional, cuya mejora en la productividad y calidad de fruto puede lograrse mediante la exploración de nuevos métodos de propagación. En ese sentido, esta investigación tuvo
García Carrasco, Gabriela Alexandra
core  

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci, Cansu Ozbayer, Ata Ozen, Gamze Zengin, Hulyam Kurt   +4 more
wiley   +1 more source