ABSTRACT Primary hyperparathyroidism (PHPT) is uncommon in the pediatric population and rarely presents with overt skeletal complications such as brown tumors. This case study describes a 16‐year‐old female who initially presented with abdominal pain and was subsequently found to have severe hypercalcemia (serum calcium 16.4 mg/dL) and markedly ...
Dosti Regmi +4 more
wiley +1 more source
The cyclin-dependent kinase inhibitor p57(Kip2) is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer [PDF]
Carboplatin remains a first-line agent in the management of epithelial ovarian cancer (EOC). Unfortunately, platinum-resistant disease ultimately occurs in most patients.
A Bali +27 more
core +1 more source
This case report highlights a rare instance of pulmonary infection caused by Tropheryma whipplei, presenting with distinctive imaging features on chest CT: multiple round or oval thick‐walled consolidations with small central cavities (approximately 1 mm in diameter) and subpleural distribution.
Yang Liu, Handan Fu
wiley +1 more source
Monoclonal gammopathy with systemic amylodosis: an evaluation of diagnostic elements [PDF]
Monoclonal gammopathies result from an overproduction of a single abnormal clone of plasma cell or B lymphocyte that produce an immunologically homogenous immunoglobulin (Ig) commonly referred to as paraprotein or monoclonal (M) protein.
Chellappah Thambiah, Subashini +2 more
core
Methylation analysis and diagnostics of Beckwith-Wiedemann syndrome in 1,000 subjects. [PDF]
BACKGROUND: Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth disorder with variable expressivity and a predisposition to tumorigenesis, results from disordered expression and/or function of imprinted genes at chromosome 11p15.5.
Berg, Jonathan +9 more
core +5 more sources
We report a case of a 29-year-old male who presented with paraesthesia and skin lesions with excessive bleeding after skin biopsy leading to hematology consultation.
S. Haider +4 more
semanticscholar +1 more source
Splenic non-Hodgkin's lymphoma without organomegaly: occult presentation with fatal course and post-mortem diagnosis [PDF]
Splenic lymphoma without splenomegaly is uncommon. We report the case of a 68-year-old female who presented with fulminant B symptoms and thrombocytopenia, only to be found to have micronodular large B-cell lymphoma of the spleen post-mortem. Diagnosis of this rare entity remains difficult and overall prognosis is poor.
Diana Garcia, Russell Patrick Gollard
openaire +3 more sources
Laryngeal lymphoma : the high and low grades of rare lymphoma involvement sites [PDF]
The larynx is an extremely rare site of involvement by lymphomatous disease.We present two cases of isolated laryngeal high-grade and another low-grade lymphoma, together with a literature review of laryngeal lymphoma management.peer ...
Azzopardi, Charles Paul +7 more
core +3 more sources
Rapidly Growing Mucinous Cystadenoma in a 13‐Year‐Old Premenarchal Female: A Case Report
ABSTRACT Mucinous cystadenomas are rare ovarian tumors in premenarchal girls but can present as rapidly growing large abdominal masses causing obstructive symptoms. Early recognition and timely surgical intervention, often requiring salpingo‐oophorectomy, are crucial to prevent complications.
Zeina Marzouk +7 more
wiley +1 more source
Umbilical Endometriosis Presenting as Cyclical Umbilical Bleeding: A Case Report
ABSTRACT Endometriosis is a benign, estrogen‐dependent condition affecting 6%–10% of women of reproductive age, typically involving pelvic organs but occasionally presenting in extrapelvic locations such as the umbilicus. We report a case of umbilical endometriosis in a nulliparous woman who developed cyclic painful bleeding and umbilical swelling 8 ...
Mujaheed Suleman +6 more
wiley +1 more source

