Results 11 to 20 of about 20,564 (250)

Polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes (POEMS syndrome): a paraneoplastic syndrome [PDF]

Oxford Medical Case Reports, 2015
POEMS syndrome (Crow–Fukase syndrome) is a rare paraneoplastic disorder. It is characterized by peripheral neuropathy, elevated vascular endothelial growth factors (VEGFs), monoclonal gammopathy, sclerotic bone lesions and Castleman disease.
Sunil Kumar, Shruti Sharma
semanticscholar   +3 more sources

Validated international definition of the thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly clinical subtype (TAFRO) of idiopathic multicentric Castleman disease

American journal of hematology/oncology, 2021
Thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly (TAFRO) syndrome is a heterogeneous entity manifesting with a constellation of symptoms described above that can occur in the context of idiopathic multicentric ...
Yoshito Nishimura, D. Fajgenbaum, S. Pierson, N. Iwaki, Asami Nishikori, M. Kawano, N. Nakamura, K. Izutsu, K. Takeuchi, M. F. Nishimura, Y. Maeda, F. Otsuka, K. Yoshizaki, É. Oksenhendler, F. Van Rhee, Y. Sato   +15 more
semanticscholar   +1 more source

Clinical and Radiological Characterisation of Patients with Mucopolysaccharidosis in a Genetic Clinic

Journal of Inborn Errors of Metabolism and Screening, 2021
The mucopolysaccharidoses (MPS) are a relatively uncommon group of inherited metabolic disorders. MPSs should be suspected in a child with coarse facies, organomegaly, recurrent respiratory tract infections, developmental delay, and hernias.
Pallavelangini Swetha, Inusha Panigrahi, Akshay Saxena, Anupriya Kaur, Rozy Thakur   +4 more
doaj   +1 more source

Thrombocytopenia, Anasarca, Myelofibrosis, Renal dysfunction, and Organomegaly (TAFRO) Syndrome Initially Diagnosed as Fibromyalgia: A Case Report

Cureus, 2023
Thrombocytopenia, Anasarca, myeloFibrosis, Renal dysfunction, and Organomegaly (TAFRO) syndrome is a rare and complex medical condition characterized by a combination of symptoms, including thrombocytopenia, anasarca, myelofibrosis, renal dysfunction ...
R. Ohta, C. Sano
semanticscholar   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease. [PDF]

Arthritis Rheumatol
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Chen LYC, Zhang L, Fajgenbaum DC.
europepmc   +2 more sources

Treatment-resistant idiopathic multicentric Castleman disease with thrombocytopenia, anasarca, fever, reticulin fibrosis, renal dysfunction, and organomegaly managed with Janus kinase inhibitors: A case report

Medicine, 2022
Rationale: Thrombocytopenia, anasarca, fever, reticulin fibrosis, renal dysfunction, and organomegaly (TAFRO) syndrome are nonmalignant but life-threatening systemic inflammatory disorders. However, many patients are refractory to treatment, resulting in
Takuya Kakutani, T. Nunokawa, N. Chinen, Y. Tamai   +3 more
semanticscholar   +1 more source

First-line Usage of Daratumumab, Lenalidomide, Dexamethasone (DRd) Combination in a Case of Castleman Disease Variant of Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes Syndrome (CD-POEMS)

HemaSphere, 2022
olyneuropathy, organomegaly, endocrinopathy, monoclo- nal gammopathy, and skin changes syndrome (POEMS) is a rare paraneoplastic syndrome of an underlying plasma cell disorder (PCD).
O. Sevindik, Y. Mutlu, B. Aydın, I. Serin   +3 more
semanticscholar   +1 more source

Characteristics of thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly syndrome: a retrospective study from a large Western cohort

British Journal of Haematology, 2021
Idiopathic multicentric Castleman disease (iMCD) is a non‐clonal inflammatory lymphoproliferative disorder of unknown origin. Recently, TAFRO syndrome (thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly) emerged as a singular variant ...
L. Maisonobe, R. Bertinchamp, L. Damian, L. Gérard, Mirlinda Berisha, S. Guillet, C. Fieschi, M. Malphettes, Jehane Fadlallah, M. Hié, B. Dunogué, V. De Wilde, F. Vandergeynst, L. Zafrani, M. Grall, N. Saada, M. Garzaro, É. Oksenhendler, L. Galicier, D. Boutboul   +19 more
semanticscholar   +1 more source

Autoimmune Lymphoproliferative Syndrome in Children with Nonmalignant Organomegaly, Chronic Immune Cytopenia, and Newly Diagnosed Lymphoma

Turkish Journal of Hematology, 2021
This study investigated the frequency of and predictive factors for autoimmune lymphoproliferative syndrome (ALPS) in children with lymphoma, chronic immune cytopenia, and nonmalignant organomegaly.
Zühre Kaya, Melek Işık, Nihan Oruklu, Serap Kirkiz, Emin Ümit Bağrıaçık, Luis M. Allende, María J. Díaz-madroñero, Raquel Ruiz-García, Faruk Güçlü Pınarlı, Pınar Göçün Uyar, Ülker Koçak   +10 more
doaj   +1 more source

A severe case of thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly syndrome with myocardial and skeletal muscle calcification despite hypocalcemia: a case report

Journal of Medical Case Reports, 2021
Background TAFRO (thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly) syndrome is a recently recognized disease with a variety of presentations of variable severity.
Shogo Minomo, Y. Fujiwara, S. Sakashita, A. Takamura, K. Nagata   +4 more
semanticscholar   +1 more source