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Organophosphate Poisoning

Seminars in Neurology, 2004
Organophosphates are commonly used as pesticides around the world. Exposures to organophosphates cause a significant number of poisonings and deaths each year. Organophosphates bind and inhibit cholinesterase enzymes. Acute toxicity manifests as a cholinergic crisis with excessive glandular secretions, altered mental status, and weakness.
Daniel E, Rusyniak, Kristine A, Nañagas
openaire   +2 more sources

Organophosphate poisoning

Annals of Emergency Medicine, 1987
Organophosphate insecticides have become increasingly popular for agricultural, industrial, and home use and represent a significant potential health risk. We have reviewed the history, pathophysiology, clinical presentation, laboratory findings, differential diagnosis, therapy, and complications of toxic exposure to organophosphates. Promp recognition
J, Tafuri, J, Roberts
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A Review of Organophosphate Poisoning

Medical Toxicology, 1988
Many organophosphate compounds are pesticides widely used for the control of insect vectors. They are not ideal agents because they lack target vector selectivity, and have caused severe toxicity and even death in humans and domestic animals. Their toxicity has been recognised since the 1930s, when they were also developed for use as chemical warfare ...
Neil A. Minton, V. S. G. Murray
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Organophosphate poisoning

Pharmacology & Therapeutics, 1993
The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. OP poisoning can occur in a variety of situations and can be accidental or suicidal. It is common in developing countries.
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Opsoclonus in Organophosphate Poisoning

Archives of Neurology, 1989
Transient opsoclonus was observed in a patient who attempted suicide with the organophosphate insecticide Malathion (diethyl[dimethoxyphosphinothioyl]thiobutanedioate). Several toxins can cause opsoclonus, and these must be considered in its differential diagnosis.
Josanne Aquilina, Patrick Pullicino
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Percutaneous Organophosphate Poisoning

Southern Medical Journal, 1987
After cutaneous application of the organophosphate insecticide Diazinon for pubic lice, our patient had symptoms of cholinergic excess, lost consciousness, and had a seizure. Because of the high index of clinical suspicion for potentially lethal organophosphate poisoning, the patient received empiric therapy with pralidoxime and atropine and completely
Sloas Dd, Halle A
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Cardiodepression in Organophosphate Poisonings

1985
During clinical epidemiological investigation of acute human organophosphate intoxication a cardiodepressive form of poisoning was recognised. It had a bad prognosis with a high incidence of lethality. The cardiodepressive form involved mechano- and electrodepression which were manifested in cardiogenic shock and sudden atrioventricular block or both ...
Marosi Gy.   +2 more
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Organophosphate and Carbamate Poisoning

Emergency Medicine Clinics of North America, 2015
Organophosphates (OPs) and carbamates have a wide variety of applications, most commonly as pesticides used to eradicate agricultural pests or control populations of disease-carrying vectors. Some OP and carbamates have therapeutic indications such as physostigmine.
Andrew King, Cynthia K. Aaron
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Therapy In Organophosphate Poisoning

Acta Clinica Belgica, 1976
SummaryThe therapy of an intoxication by cholinesterase-inhibitors consists of the administration of atropine for symptomatic treatment, of the administration of oximes as a causal therapy and of general supportive measures. The dose of atropine is chosen according to the intensity of the poisoning; the therapeutic use of oximes is briefly discussed.
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Brain Involvement in Organophosphate Poisoning

Environmental Research, 1997
Organophosphate poisonings cause substantial morbidity and mortality worldwide; however, the neurological effects have not been clearly established. We have studied cerebral perfusion to investigate neurotoxic effects. Clinical effects, plasma cholinesterase activity, and brain single photon emission computerization tomography (SPECT) data were ...
Ozyurt, G, Yilmazlar, A
openaire   +4 more sources

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