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Organophosphate-Induced Delayed Polyneuropathy
Toxicological Reviews, 2005Organophosphate-induced delayed polyneuropathy (OPIDP) is a rare toxicity resulting from exposure to certain organophosphorus (OP) esters. It is characterised by distal degeneration of some axons of both the peripheral and central nervous systems occurring 1-4 weeks after single or short-term exposures.
M. Lotti, A. Moretto
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Organophosphate polyneuropathy
Neurology, 1984Organophosphorus-induced delayed polyneuropathy (OPIDP) is initiated by the phosphorylation of a protein neurotoxic esterase (NTE) in the nervous system. A second step, the "aging" of the phosphoryl-enzyme complex, is required to produce the toxic effect.
LOTTI, MARCELLO, BECKER CE, AMINOFF MJ
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Organophosphates, Serine Esterase Inhibition, and Modeling of Organophosphate Toxicity
Toxicological Sciences, 2004The highlighted article in this issue (Ashani and Pistinner, "Estimation of the Upper Limit of Human Butyrylcholinesterase Dose Required for Protection against Organophosphates toxicity: A Mathematically Based Toxicokinetic Model") is an innovative approach to modeling the amount of protective enzyme, human butyrylcholinesterase, that could be ...
Janice, Chambers, Seth F, Oppenheimer
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Pharmacology of organophosphates
Journal of Applied Toxicology, 1994AbstractThe cholinergic nerve fibers, which employ acetylcholine (ACh) as a neurohumoral transmitter, and the results of their activation are listed. The reactions between the enzyme acetylcholinesterase (AChE), its natural substrate, ACh, and the various types of inhibitors are described.
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Nursing RSA = Verpleging RSA, 1994
The number of patients admitted to Intensive Care Units with organophosphate poisoning are a source of concern. Also distressing is the fact that organophosphates are often being used in suicide attempts. It is therefore imperative that the nurse acquires and retains the necessary skills for caring for these patients.
S, Blauwol +2 more
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The number of patients admitted to Intensive Care Units with organophosphate poisoning are a source of concern. Also distressing is the fact that organophosphates are often being used in suicide attempts. It is therefore imperative that the nurse acquires and retains the necessary skills for caring for these patients.
S, Blauwol +2 more
openaire +1 more source