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Cumulative exposure to acetylcholinesterase inhibiting compounds in the Dutch population and young children [PDF]

, 2003
Klaveren, J.D., van, Boon, P.E.
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Bio-sensing of organophosphorus pesticides: A review

Biosensors and Bioelectronics, 2019
Organophosphorus (OP) pesticides have been used widely as agricultural and household pest control agents for almost five decades and persist in our water resources, fruits, vegetables and processed food as health and environmental hazardous compounds. Thus, detection of these harmful OP pesticides at an ease with high sensitivity and selectivity is the
Ashish Malik, C S Pundir
exaly   +3 more sources

Chlorination of organophosphorus pesticides in natural waters

Journal of Hazardous Materials, 2008
Unknown second-order rate constants for the reactions of three organophosphorus pesticides (chlorpyrifos, chlorfenvinfos and diazinon) with chlorine were determined in the present study, and the influence of pH and temperature was established. It was found that an increase in the pH provides a negative effect on the pesticides degradation rates ...
Francisco J Real, Juan L Acero, F Javier Benitez   +2 more
exaly   +3 more sources

ALKYLATION OF DNA BY ORGANOPHOSPHORUS PESTICIDES

Acta Pharmacologica et Toxicologica, 1979
Methods for the detection of in vivo alkylation of nucleic acids are discussed. Alkylation of mammalian DNA at N‐7 of guanine provides the most sensitive and least equivocal evidence of methylation by an exogenous chemical or its metabolite. No 7‐methylguanine was detected in the combined DNA from the lungs, livers, hearts, brains, kidneys, testes and ...
M F, Wooder, A S, Wright
openaire   +2 more sources

Estrogenicity of Organophosphorus and Pyrethroid Pesticides

Journal of Toxicology and Environmental Health, Part A, 2002
Although organophosphorus and pyrethroid pesticides are considered environmental contaminants, their estrogenic potentials are still ubiquitous and unclear. The present study was undertaken to evaluate the estrogenic activities of nine pesticides (phoxim, malathion, monocrotophos, dimethoate, opunal, fenvalerate, cypermethrin, permethrin, and ...
Haiyan, Chen, Jigao, Xiao, Gang, Hu, Jianwei, Zhou, Hang, Xiao, Xinru, Wang   +5 more
openaire   +2 more sources

Biodegradation of organophosphorus pesticides by surface-expressed organophosphorus hydrolase

Nature Biotechnology, 1997
Organophosphorus hydrolase (OPH) was displayed and anchored onto the surface of Escherichia coli using an Lpp-OmpA fusion system. Production of the fusion proteins in membrane fractions was verified by immunoblotting with OmpA antisera. Inclusion of the organophosphorus hydrolase signal sequence was necessary for achieving enzymatic activity on the ...
R D, Richins, I, Kaneva, A, Mulchandani, W, Chen   +3 more
openaire   +2 more sources

Cumulative risk assessment of the intake of organophosphorus and carbamate pesticides in the Danish diet

Food Additives and Contaminants, 2003
The aim of the study is to evaluate the potential cumulative effects of organophosphorus and carbamate pesticides that act through a common mechanism of toxicity, and to assess the long- and short-term risks for the Danish population.
Kit Granby
exaly   +2 more sources

Determination of organophosphorus pesticides in water

1969
Increasing use of organic chemicals for agricultural purposes has caused great concern in recent years. Rachel Carson (1962) was one of the first to focus public attention on the possible hazards connected with pesticide use. Because of this concern, much work (Dugan et al.
G, Zweig, J M, Devine
openaire   +2 more sources

Hepatic injury and disturbed amino acid metabolism in mice following prolonged exposure to organophosphorus pesticides

Human and Experimental Toxicology, 1999
1 Chronic occupational exposure to organophosphorus and carbamate-type pesticides significantly inhibits acetylcholinesterase activity and causes morbidity. This study on mice was designed to evaluate their amino profile and to identify signs of hepatic
James Gomes
exaly   +2 more sources

Mammalian toxicology of organophosphorus pesticides

Journal of Toxicology and Environmental Health, 1994
Organophosphorus compounds have been utilized as pesticides for almost five decades. They continue to be used as insecticides, helminthicides, ascaricides, nematocides, and to a lesser degree as fungicides and herbicides. While they have been and continue to be extremely useful in agricultural pest control throughout the world, their extensive use has ...
openaire   +2 more sources