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Management of Organophosphorus Poisoning: Standard Treatment and Beyond.
Critical Care Clinics, 2021Organophosphorus (OP) compounds remain a leading cause of self-poisoning and mortality, especially in South East Asia, China, and Africa. Organophosphorus causes an acute cholinergic syndrome by inhibiting acetylcholinesterase.
Sakib Aman, Shrebash Paul, F. Chowdhury
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Acute Organophosphorus Poisoning
Clinica Chimica Acta, 2014Acute organophosphorus poisoning continues to be a detrimental problem and a potential cause of mortality especially in developing countries. Inhibition of acetylcholinesterase enzyme is the main mechanism of toxicity of such pesticides and measurement of acetylcholinesterase activity is the commonly used laboratory diagnosis approved for the purpose ...
Rajasri Bhattacharya +2 more
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Management of Acute Organophosphorus Pesticide Poisoning [PDF]
Lancet, The, 2008 SummaryOrganophosphorus pesticide self-poisoning is an important clinical problem in rural regions of the developing world, and kills an estimated 200 000 people every year.
Nicholas A. Buckley +2 more
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Pralidoxime for Organophosphorus Poisoning
Lancet, The, 1992T J Meredith, J A Vale, T C Marrs
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Organophosphorus compound poisoning.
Journal of Association of Physicians of India, 2022This datasheet on organophosphorus compound poisoning covers Identity, Hosts/Species Affected, Diagnosis.
H. Aleem
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[Organophosphorus poisoning: Towards enzymatic treatments].
Annales Pharmaceutiques Françaises, 2019Organophosphorus compounds (OP) are toxic molecules developed as insecticides and chemical warfare nerve agents (CWNAs). Most OP are neurotoxic and act as nervous system disruptors by blocking cholinergic transmission.
P. Jacquet +3 more
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Organophosphorus and carbamate insecticide poisoning
2015Both organophosphorus (OP) and carbamate insecticides inhibit acetylcholinesterase (AChE), which results in accumulation of acetylcholine (ACh) at autonomic and some central synapses and at autonomic postganglionic and neuromuscular junctions. As a consequence, ACh binds to, and stimulates, muscarinic and nicotinic receptors, thereby producing ...
Allister, Vale, Marcello, Lotti
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Pyridinium oximes in the treatment of poisoning with organophosphorus compounds
Handbook of Toxicology of Chemical Warfare Agents, 2020Organophosphorus (OP) compounds have been used as pesticides and have been developed as warfare nerve agents such as tabun, soman, sarin, VX, and others.
M. Jokanović +3 more
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PHYSIOLOGICAL EVENTS IN ORGANOPHOSPHORUS POISONING
Canadian Journal of Biochemistry and Physiology, 1959Null
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