Results 41 to 50 of about 9,872 (204)

Genotoxicity and Cytotoxicity Exerted by Pesticides in Different Biotic Matrices-An Overview of More Than a Decade of Experimental Evaluation [PDF]

, 2014
Agrochemicals represent one of the most important sources of environmental pollution. Although attempts to reduce agrochemical use through organic agricultural practices and the use of other technologies to control pests continue, the problem is still
Larramendy, Marcelo Luis, Nikoloff, Noelia, Ruiz de Arcaute, Celeste, Soloneski, Sonia Maria Elsa   +3 more
core   +2 more sources

Organophosphorus poisoning and anaesthesia [PDF]

Anaesthesia, 1999
Organophosphorus compounds, used as insecticides and agents of chemical warfare, are a major global cause of health problems. These irreversible inhibitors of cholinesterase produce three well‐recognised clinical entities: the initial cholinergic phase, which is a medical emergency often requiring management in an intensive care unit; the intermediate ...
openaire   +2 more sources

The key role of magnesium sulfate in the management of organophosphorus pesticide poisoning: a scoping literature review [PDF]

Clinical and Experimental Emergency Medicine
Organophosphorus agents are easily absorbed via respiratory, gastrointestinal, and dermal routes, and inhibit the acetylcholinesterase (AChE) enzyme, which is responsible for the majority of toxicity caused by organophosphates in the body.
Zahra Nekoukar, Homa Talabaki, Zakaria Zakariaei, Mahdi Mesri, Hossein Azadeh   +4 more
doaj   +1 more source

Self injection of Dichlorvos, an Organophosphorus Compound [PDF]

, 2008
We report two patients who injected themselves a strong organophosphate compound, dichlorvas, and showed the typical clinical picture of organophosphate intoxication. There are very few case reports of parenteral organophosphorous poisoning.
DM, Mahesh, Gupta, Dalip, Kaushal, Satinder Singh, Raina, Sujeet, Sood, Vivek   +4 more
core   +1 more source

OpdA, a bacterial organophosphorus hydrolase, prevents lethality in rats after poisoning with highly toxic organophosphorus pesticides [PDF]

, 2008
Organophosphorus (OP) pesticides poison more than 3,000,000 people every year in the developing world, mostly through intentional self-poisoning. Advances in medical therapy for OP poisoning have lagged, and current treatment is not highly effective with
Adie, Ahmad, Bruyndonckx, Buckley, Chip Gresham, Colin Scott, Dunn, Eddleston, Eddleston, Eddleston, Eyer, Fears, Horne, Jackson, Jeyaratnam, John Oakeshott, Lewis, Mazur, Michael Eddleston, Ortigoza-Ferado, Peng, Phillips, Sogorb, Steven B. Bird, Tara D. Sutherland, Van der Hoek, Yang   +26 more
core   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva, Wellington V. dos Santos, Vinicius C. V. da Rocha, Joyce S. F. D. de Almeida, Leandro B. Bernardo, Taynara Carvalho-Silva, Cintia N. Ferreira, Angelo A. T. da Silva, Alessandro B. C. Simas, Eugenie Nepovimova, Kamil Kuča, Tanos C. C. França, Samir F. de A. Cavalcante   +14 more
doaj   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

The Long-Term Effects of Organophosphates Poisoning as a Risk Factor of CVDs: A Nationwide Population-Based Cohort Study. [PDF]

PLoS ONE, 2015
Organophosphorus pesticides are widely used throughout the world. Because of their ease of availability, organophosphorus compounds are commonly used for self-poisoning in developing countries. The acute effects of exposure to organophosphorus pesticides
Dong-Zong Hung, Hao-Jan Yang, Yu-Fen Li, Cheng-Li Lin, Shih-Yu Chang, Fung-Chang Sung, Sally C W Tai   +6 more
doaj   +1 more source

Crystal Facets Reactivity in Metal–Organic Frameworks

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
In this mini review, it is highlighted how the crystal facets reactivity of metal–organic frameworks can be dictated by bond strength, surface functionality, particle size, defect density, or crystal morphology. Precise control of these parameters enables deliberate exposure of crystal facets, leading to enhanced crystal surface accessibility and ...
Emilio Borrego‐Marin, Jorge A. R. Navarro   +1 more
wiley   +1 more source