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Complexes of Water Soluble Polymers and Organoplatinum Compounds as Potential Time-Release Antitumor Formulations

1988
The serendipitous discovery of the biological activity of cis-dichlorodi-ammineplatinum(II) [“Cisplatin”] by Rosenberg in 1965 spawned an intensive investigation of the chemical and biological properties of this compound and its derivatives (1–6). Cisplatin and derivatives represent a class of very effective, broad spectrum antitumor agents (6).
B. A. Howell   +5 more
openaire   +1 more source

Phase II trial of zeniplatin (CL 286 558), a new patinum compound, in patients with advanced ovarian cancer previously treated with organoplatinum-based therapy

Journal of Cancer Research and Clinical Oncology, 1993
There is a critical need to find new chemotherapeutic agents that are active in platinum-refractory ovarian cancer. A phase II trial of zeniplatin (CL 286,558), a third-generation platinum compound, was conducted in 31 patients with advanced ovarian cancer to examine the safety and activity of the agent when used as a salvage treatment in individuals ...
Maurie Markman   +14 more
openaire   +2 more sources

ChemInform Abstract: Comparison of Metal‐Hydrogen, ‐Oxygen, ‐Nitrogen and ‐Carbon Bond Strengths and Evaluation of Functional Group Additivity Principles for Organoruthenium and Organoplatinum Compounds.

ChemInform, 1989
AbstractThe relative bond strengths for the complexes (I) and (II) are determined from equilibrium measurements.
H. E. BRYNDZA   +5 more
openaire   +1 more source

ChemInform Abstract: ORGANOPLATINUM COMPOUNDS. II. REDUCTIVE ELIMINATION OF METHYL AZIDE FROM TETRAMERIC TRIMETHYLAZIDO PLATINUM WITH TRIMETHYL PHOSPHITE YIELDING CIS‐DIMETHYL BIS(TRIMETHYL PHOSPHITE)PLATINUM

Chemischer Informationsdienst, 1976
AbstractDer Komplex (III) wird entsprechend dem Formelschema auf 3 unabhängigen Wegen dargestellt.
B. NERUDA, J. LOERBERTH
openaire   +1 more source

ChemInform Abstract: THE REACTION BETWEEN ORGANOMERCURIALS AND PLATINUM(0)PHOSPHINE COMPLEXES, A NEW VERSATILE SYNTHESIS OF SIGMA‐BONDED ORGANOPLATINUM(II) COMPOUNDS

Chemischer Informationsdienst, 1974
AbstractDurch Umsetzung der Triphenylphosphinplatin(0)‐Komplexe (I) mit Organoquecksilberverbindungen (II) werden die σ‐Organoplatin(II)‐Komplexe (III) gebildet.
V. I. SOKOLOV   +3 more
openaire   +1 more source

Electron impact ionisation and other molecular processes for organoplatinum compounds

Molecular Physics, 2022
Rakesh Bhavsar   +3 more
openaire   +1 more source

Platinum-carbon bond formation by cyclometallation and oxidative addition reactivity of organoplatinum compounds

1988
The work described in this thesis stems from the observation that a pyrazolyl group in Me2Pt(HCpz3) umdergoes a Cyclometallation reaction when heated in neat pyridine, giving rise to a NC- coordination mode, which is uncommon for flexible carbon bridged maltidentate ligands....
openaire   +1 more source

Organoplatinum compounds

Journal of Organometallic Chemistry, 1977
Boris Neruda   +2 more
openaire   +1 more source

Organoplatinum compounds

Journal of Organometallic Chemistry, 1976
Boris Neruda, Jorg Lörberth
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Organoplatinum compounds

Journal of Organometallic Chemistry, 1988
W. Massa   +3 more
openaire   +1 more source

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