Results 141 to 150 of about 1,274,253 (261)
Nitrogen and Phosphorus Additions Alleviate Nitrogen Limitation in <i>Pinus yunnanensis</i> Seedlings by Reshaping Organ-Specific Stoichiometry. [PDF]
Li N, Liao J, Su X, Li X, Cai N, Xu Y.
europepmc +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Rapid 3D Immunolabeling and Light Sheet Microscopy for Quantitative Analysis of Intact Tissues. [PDF]
Chen J +5 more
europepmc +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
First-in-human radiation dosimetry of the GRPR antagonist [<sup>68</sup>Ga]Ga-NOTA-PEG<sub>2</sub>-RM26 in patients with prostate and breast cancer. [PDF]
Bjäreback A +7 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Integrated Metabolomics and Molecular Docking Reveal Spatial and Developmental Variations in Flavor and Bioactive Constituents of <i>Lonicera japonica</i> Flos. [PDF]
Feng W +6 more
europepmc +1 more source
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source

