Results 61 to 70 of about 1,669,332 (299)
Baby Octopuses Grow Hundreds of Mystery Organs Only to Lose Them as They Grow Up
[Science alert] Your internal organs grow and change throughout your life, but rarely do they vanish without a trace. For baby octopuses, things are not so simple.
Villanueva, Roger
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Proposed Market for Human Organs
During the last decade there have been enormous advances in the transplantation of vital human organs -- in particular, the kidney, lung, heart, liver, pancreas, and small intestine.
Spurr, Stephen J.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Modern opportunities of regenerative medicine: biofabrication of hollow organs [PDF]
For the treatment of patients with organs damaged or removed by medical indications, transplantation from donors is currently used. High risks of death, lifelong immunosuppression and an acute shortage of donor organs worsen the prospect of their use ...
S. V. Popov +5 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
This paper recognizes a specific correspondence between biological evolution and technological development and on this basis tries to set up a semiotic approach to the evolutionary phenomenon of exaptation.
Davide Weible
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The theory of "Manastattvada" is famous in the Indian theistic philosophy tradition. It has been rendered by the believer masters in different ways, such as the masters of the Naiyayik sect in the sense and atomic form, the Sankhya masters combined the ...
Janardan Bhoi
doaj

