Results 111 to 120 of about 1,284,838 (261)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

"APPLICATION OF DOSIMETRY METHODS FOR INTERNAL ORGANS EXPOSURE AND POSSIBLE INFLUENCE TO REMOTE EFFECTS "

Eurasian Physical Technical Journal, 2018
Internal dosimetry study is conducted during rats exposure by dust of 56Mn powder during experiment to study exposure effect in Kurchatov reactor complex Baical-1 (Kurchatov city, East-Kazakhstan region).
Y.T. Zhunussov, K.Sh. Zhumadilov, N.Zh. Chaizhunusova, N.B. Sayakenov, D.M. Shabdarbaeva, V.S. Gnyrya, А.S. Аzimkhanov, V.F. Stepanenko, N. Fujimoto, K. Shichijo, M. Hoshi   +10 more
doaj  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Hidden caveats in tick dissection: engorgement level and complex tracheal network architecture compromise internal organ integrity. [PDF]

J Insect Sci
Dhakal P, Fu Y, Yan Z, Yang M, Ma C, Wu Y, Wang J, Wang Q, Zhang L.   +8 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Regulatory approach to manipulated organs in Europe: preserving human organs as non-commercial goods. [PDF]

Transpl Int
Cuende N, Izeta A, Domínguez-Gil B.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Organ-Specific Perfusion Response to Adenosine as Measured Using Total-Body PET. [PDF]

J Nucl Med
Kärpijoki H, Tuisku J, Palonen S, Han C, Iida H, Klén R, Oikonen V, Teuho J, Saraste A, Nummenmaa L, Nesterov SV, Maaniitty T, Knuuti J.   +12 more
europepmc   +1 more source

Organized organization [PDF]

, 2008
Göran Ahrne, Nils Brunsson
openaire   +1 more source