Results 61 to 70 of about 1,669,332 (299)

Baby Octopuses Grow Hundreds of Mystery Organs Only to Lose Them as They Grow Up

open access: yes, 2021
[Science alert] Your internal organs grow and change throughout your life, but rarely do they vanish without a trace. For baby octopuses, things are not so simple.
Villanueva, Roger
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Proposed Market for Human Organs

open access: yes, 1993
During the last decade there have been enormous advances in the transplantation of vital human organs -- in particular, the kidney, lung, heart, liver, pancreas, and small intestine.
Spurr, Stephen J.
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Modern opportunities of regenerative medicine: biofabrication of hollow organs [PDF]

open access: yes, 2019
For the treatment of patients with organs damaged or removed by medical indications, transplantation from donors is currently used. High risks of death, lifelong immunosuppression and an acute shortage of donor organs worsen the prospect of their use ...
S. V. Popov   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Approaching a semiotics of exaptation: At the intersection between biological evolution and technological development

open access: yesSign Systems Studies, 2013
This paper recognizes a specific correspondence between biological evolution and technological development and on this basis tries to set up a semiotic approach to the evolutionary phenomenon of exaptation.
Davide Weible
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mind in Theistic Philosophies

open access: yesPrachi Prajna, 2022
The theory of "Manastattvada" is famous in the Indian theistic philosophy tradition. It has been rendered by the believer masters in different ways, such as the masters of the Naiyayik sect in the sense and atomic form, the Sankhya masters combined the ...
Janardan Bhoi
doaj  

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