Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Ideal Surgical Incision Lines Minimizing Tension: A Proposal Based on Observations of Hypertrophic Scars and Keloids. [PDF]
Huang C, Quong WL, Kamii Y, Ogawa R.
europepmc +1 more source
Result-oriented PSS Modular Design Method based on FDSM
Xiuli Geng, Yunting Jin, Yongzheng Zhang
openalex +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The Influence of Pulsed Superimposed DC Electric Field Synergistically Inducing Orientation Arrangement of BNNSs on Thermal Properties of Epoxy Composites. [PDF]
Wang X +6 more
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cost-effectiveness of the addition of sintilimab as a first-line therapy for locally advanced or metastatic oesophageal squamous cell carcinoma: a Chinese healthcare system perspective. [PDF]
Yu C +9 more
europepmc +1 more source
A Human-Oriented Cooperative Driving Approach: Integrating Driving Intention, State, and Conflict [PDF]
Qin Wang +6 more
openalex
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Acellular Dermal Graft Augmentation Technique for Arthroscopic Rotator Cuff Repair. [PDF]
Pomenta MV +5 more
europepmc +1 more source

