Results 41 to 50 of about 2,767,599 (298)
Advanced Science, EarlyView.VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu +13 more
wiley +1 more source
Further studies on the morphology of three species of Rhopalopsole (Plecoptera, Leuctridae) [PDF]
Biodiversity Data JournalRhopalopsole Klapálek, 1912, is a species-rich genus in the family Leuctridae, with more than 80 valid species known from the Oriental and eastern Palaearctic Regions.We recently examined specimens of Rhopalopsole Klapálek, 1912 from Hubei and Guizhou ...
Xiao Yang, Yu-Zhou Du
doaj +3 more sources
Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Lea, 2013 This article aims at showing the vital role of poetry in Estonia today. Piera Mattei focuses in particular on the works of four contemporary poets and introduces their main features.
Piera Mattei
doaj +1 more source
Imaging scattering orientation with spatial frequency domain imaging [PDF]
Journal of Biomedical Optics, 2011 Optical imaging techniques based on multiple light scattering generally have poor sensitivity to the orientation and direction of microscopic light scattering structures. In order to address this limitation, we introduce a spatial frequency domain method for imaging contrast from oriented scattering structures by measuring the angular-dependence of ...
Konecky, Soren D +3 more
openaire +4 more sources
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Advanced Science, EarlyView.Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source
Racializing “Oriental” Manliness: From Colonial Contexts to Cologne
Islamophobia Studies Journal, 2017 We propose a co-authored, interdisciplinary paper examining the durability of Islamophobic stereotypes connected to men from the MENA region and their specific forms of “manliness”.
Zuher Jazmati, Nina Studer
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Advanced Science, EarlyView.A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li +13 more
wiley +1 more source
La femme-musulmane et la littérature
Altre Modernità, 2011 Representations of Oriental woman have evolved through centuries. Pictured as a sexual object by Orientalists in 18th and 19th centuries, or to serve Arab nationalisms (Tunisia, Algeria) in the 20th century, these images have been reconfigured after 9/11
Hayatte Lakraâ
doaj +1 more source
Towards a Compositional Framework for Describing Human Phenotypes
Advanced Science, EarlyView.The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu +11 more
wiley +1 more source