Results 61 to 70 of about 2,100,534 (347)

A Fast Deep Learning Approach for Beam Orientation Optimization for Prostate Cancer Treated with Intensity Modulated Radiation Therapy.

Medical Physics (Lancaster), 2019
PURPOSE Beam orientation selection, whether manual or protocol-based, is the current clinical standard in radiation therapy treatment planning, but it is tedious and can yield suboptimal results.
Azar Sadeghnejad Barkousaraie, Olalekan P. Ogunmolu, Steve B. Jiang, D. Nguyen   +3 more
semanticscholar   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

In situ atomic-level observation of the formation of platinum silicide at platinum-silicon oxide interfaces under electron irradiation

AIP Advances, 2018
In situ atomic-level observation of the formation of Pt2Si at Pt/SiOx interface by electronic excitation under electron irradiation was performed by using scanning transmission electron microscopy.
Takeshi Nagase, Ryo Yamashita, Jung-Goo Lee   +2 more
doaj   +1 more source

Orientation Invariant Sensorimotor Object Recognition Using Cortical Grid Cells

Frontiers in Neural Circuits, 2022
Grid cells enable efficient modeling of locations and movement through path integration. Recent work suggests that the brain might use similar mechanisms to learn the structure of objects and environments through sensorimotor processing.
Kalvyn Roux, David van den Heever, David van den Heever   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Multi-scale Physical Properties of NGC 6334 as Revealed by Local Relative Orientations between Magnetic Fields, Density Gradients, Velocity Gradients, and Gravity

The Astrophysical Journal, 2023
We present ALMA dust polarization and molecular line observations toward four clumps (I(N), I, IV, and V) in the massive star-forming region NGC 6334.
Junhao Liu, Qizhou Zhang, Patrick M. Koch, Hauyu Baobab Liu, Zhi-Yun Li, Shanghuo Li, Josep Miquel Girart, Huei-Ru Vivien Chen, Tao-Chung Ching, Paul T. P. Ho, Shih-Ping Lai, Keping Qiu, Ramprasad Rao, Ya-wen Tang   +13 more
doaj   +1 more source

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

Advanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat, Mojtaba Karamimoghadam, Mohammadreza Lalegani Dezaki, Ali Zolfagharian, Giuseppe Casalino, Antonio Mateo, Mahdi Bodaghi   +6 more
wiley   +1 more source

Parallel Alignments between Magnetic Fields and Dense Structures in the Central Molecular Zone

The Astrophysical Journal
The recent Far-Infrared Polarimetric Large-Area Central Molecular Zone Exploration (FIREPLACE) survey with SOFIA has mapped plane-of-sky magnetic field orientations within the Central Molecular Zone (CMZ) of the Milky Way.
Xing Pan, Qizhou Zhang, Keping Qiu, Dylan M. Paré, David T. Chuss, Natalie O. Butterfield, Robin G. Tress, Mattia C. Sormani, Yuping Tang, Steven N. Longmore, Thushara Pillai   +10 more
doaj   +1 more source

Column-Oriented Datalog on the GPU

Proceedings of the AAAI Conference on Artificial Intelligence
Datalog is a logic programming language widely used in knowledge representation and reasoning (KRR), program analysis, and social media mining due to its expressiveness and high performance. Traditionally, Datalog engines use either row-oriented or column-oriented storage.
Sun, Yihao, Kumar, Sidharth, Gilray, Thomas, Micinski, Kristopher   +3 more
openaire   +2 more sources

Orientation and Color Columns in Monkey Visual Cortex [PDF]

Cerebral Cortex, 2002
The literature on orientation and color columns in monkey visual cortex is reviewed. The orientation column model most consistent with existing data is one containing 'stripes' of alternating positive and negative orientation 'singularities' (cytochrome oxidase blobs) which run along the centers of ocular dominance (OD) columns, with horizontal and ...
openaire   +2 more sources