Results 61 to 70 of about 714,937 (283)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Improved Complementary Filters for Estimation of Heading and Attitude Angles in Accelerated Motion [PDF]

مکانیک هوافضا, 2023
In this paper, a method for improving the performance of Complementary filter in the Attitude and Heading Reference System for estimating the orientation in accelerated movements is presented.
Ali Namvar, Mohammad Mahdi Dehghan, Hossein Nourmohammadi, Mohammadali Alirezapouri   +3 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Effects of repetitive low-acceleration impacts on attitude estimation with micro-electromechanical inertial measurement units

Frontiers in Robotics and AI, 2023
Inertial Measurement Units are present in several applications in aerospace, unmanned vehicle navigation, legged robots, and human motion tracking systems, due to their ability to estimate a body’s acceleration, orientation and angular rate.
Federico Allione, Federico Allione, Juan D. Gamba, Antonios E. Gkikakis, Roy Featherstone, Darwin Caldwell   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

DOES: A Deep Learning-Based Approach to Estimate Roll and Pitch at Sea

IEEE Access, 2022
The use of Attitude and Heading Reference Systems (AHRS) for orientation estimation is now common practice in a wide range of applications, e.g., robotics and human motion tracking, aerial vehicles and aerospace, gaming and virtual reality, indoor ...
Fabiana Di Ciaccio, Paolo Russo, Salvatore Troisi   +2 more
doaj   +1 more source

Multi-Array 5G V2V Relative Positioning: Performance Bounds

, 2019
We study the performance bounds of vehicle-to-vehicle (V2V) relative positioning for vehicles with multiple antenna arrays. The Cram\'{e}r-Rao bound for the estimation of the relative position and the orientation of the Tx vehicle is derived, when angle ...
García, Mario H. Castañeda, Kakkavas, Anastasios, Nossek, Josef A., Stirling-Gallacher, Richard A.   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

ESTIMATION OF FIBRE ORIENTATION FROM DIGITAL IMAGES

Image Analysis & Stereology, 2011
In this paper, estimation of fibre orientation is studied for fibre systems observable as a blurred greyscale image. The estimation method is based on scaled variograms observed along a set of sampling lines in different directions. The parameters of the orientation distribution are obtained numerically. Simulated data are used to study the statistical
Kärkkäinen, Salme, Jensen, Eva B. Vedel   +1 more
openaire   +4 more sources