Results 181 to 190 of about 4,261 (215)
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PREVALENCE OF RELATIVE BRADYCARDIA IN ORIENTIA TSUTSUGAMUSHI INFECTION
The American Journal of Tropical Medicine and Hygiene, 2003We investigated 100 febrile patients infected with Orientia tsutsugamushi (the etiologic agent of scrub typhus) for the presence of relative bradycardia, defined as in increase in heart rate of < 10 beats/minutes/1°C increase in temperature. The median heart rate response for the entire febrile scrub typhus population was 9.3 beats/minute/°C and the
David M, Aronoff, George, Watt
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Subversion of host cell signaling by Orientia tsutsugamushi
Microbes and Infection, 2011Progress has been made in deciphering the mechanisms on Orientia tsutsugamushi-host interaction. The genome sequencing, microarray and proteomic analyses of this ancient bacterium have provided a wealth of new information. This paper reviews the general characteristics of O.
Yan, Ge, Yasuko, Rikihisa
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Scrub typhus and antibiotic-resistant Orientia tsutsugamushi
Expert Review of Anti-infective Therapy, 2021Introduction: Scrub typhus is one of the most underdiagnosed and under-reported febrile illnesses requiring hospitalization, mainly occurring in Southeast and East Asia and the Pacific Islands, in an area referred to as the 'Tsutsugamushi Triangle.' Scrub typhus is a zoonotic rickettsial disease that is transmitted to humans by trombiculid mites.Areas ...
Chin-Te, Lu +2 more
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Molecular detection of Orientia tsutsugamushi strains circulating in Nagaland
Indian Journal of Medical Microbiology, 2022The antigenic heterogeneity of Orientia in India is still unknown in many disease endemic areas. The present study aims to characterize the strains of O. tsutsugamushi circulating in Nagaland, Northeast India. Two patients clinically diagnosed with ST and hospitalized in Mon district hospital, Nagaland were identified from whom eschar tissues were ...
Siraj A, Khan +4 more
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An epitope shared by cellular cytokeratin and Orientia tsutsugamushi
Microbial Pathogenesis, 2006Many microbial pathogens have epitopes shared with host cell components and these epitopes may induce transient or longer-term tissue-damaging autoantibody responses. We observed that several mouse monoclonal antibodies (MAbs) raised against Orientia tsutsugamushi were also reactive with host cells.
Mi-Jeong, Kim +2 more
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Biology of Orientia tsutsugamushi
2016Orientia tsutsugamushi is an intracellular, Gram-negative bacterium belonging to order Rickettsiales and is the causative agent of scrub typhus. The organism is transmitted to human host by chiggers; the larval stage of trombiculid mites and transovarial transmission is thought to be the only mechanism for its maintenance in the mites.
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OCCURRENCE OF ORIENTIA TSUTSUGAMUSHI IN SMALL MAMMALS FROM THAILAND
The American Journal of Tropical Medicine and Hygiene, 2003Extensive sampling of small mammals was conducted in eight provinces of Thailand between September 9, 1992 and April 29, 2001. A total of 3,498 specimens representing 22 species were collected. Eighty-eight percent (3,089 of 3,498) of the animals were collected from a region in Chiangrai Province, which is commonly recognized as endemic for human scrub
Russell E, Coleman +12 more
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Global gene expression profile of Orientia tsutsugamushi
PROTEOMICS, 2010AbstractOrientia tsutsugamushi, an obligate intracellular bacterium, is the causative agent of Scrub typhus. The control mechanisms for bacterial gene expression are largely unknown. Here, the global gene expression of O. tsutsugamushi within eukaryotic cells was examined using a microarray and proteomic approaches for the first time.
Cho, BA +14 more
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Role of Syndecan-4 in the cellular invasion of Orientia tsutsugamushi
Microbial Pathogenesis, 2004Cell surface heparan sulfate proteoglycans (HSPGs) play a critical role in the cellular invasion of intracellular bacteria and are presumed to have a role in the infection of host cells by Orientia tsutsugamushi. Previously, we showed that O. tsutsugamushi infection decreased markedly after treating host cells with heparinase, which suggests that HSPGs
Hang-Rae, Kim +2 more
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Antigenic types of Orientia tsutsugamushi in Malaysia.
The Southeast Asian journal of tropical medicine and public health, 2003The seroprevalence of various Orientia tsutsugamushi (OT) strains among Malaysian patients with suspected scrub typhus infections was determined using an indirect immunoperoxidase (IIP) assay. IgG against a single OT strain were detected in six sera (3 Karp, 1 Gilliam and 2 TC586), whereas IgM antibodies against a single OT strain (Gilliam) were noted ...
S T, Tay, M Y, Rohani, T M, Ho, S, Devi
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