Results 241 to 250 of about 3,067,292 (342)
Geochemistry and the Origin of Life (Kvenvolden, Keith A., ed.) [PDF]
, 1976 John F. Wehmiller
openalex +1 more source
Challenges of religious life in diasporic Muslim communities of Western Balkan origin
, 2022 Senad Hevešević
openalex +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
On the Roles of Protein Intrinsic Disorder in the Origin of Life and Evolution. [PDF]
Life (Basel)Uversky VN.
europepmc +1 more source
Emergence of Order in Origin-of-Life Scenarios on Mineral Surfaces: Polyglycine Chains on Silica. [PDF]
Langmuir, 2022 El Samrout O +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Autocatalytic Selection as a Driver for the Origin of Life. [PDF]
Life (Basel)Williamson MP.
europepmc +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source