Results 241 to 250 of about 5,461,980 (349)
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Autocatalytic Selection as a Driver for the Origin of Life. [PDF]
Life (Basel)Williamson MP.
europepmc +1 more source
Walt Whitman's "There Was a Child Went Forth": The Image of "Edges" in the Origins of Life [PDF]
, 1985 E. Lâle Demirtürk
openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
Pinpointing Conditions for a Metabolic Origin of Life: Underlying Mechanisms and the Role of Coenzymes. [PDF]
Acc Chem ResZimmermann J +3 more
europepmc +1 more source
From the origin of life to pandemics: emergent phenomena in complex systems. [PDF]
Philos Trans A Math Phys Eng Sci, 2022 Artime O, De Domenico M.
europepmc +1 more source