Results 21 to 30 of about 7,449,331 (271)
Punishment in Pre-Colonial Indigenous Societies in North America [original paper] [PDF]
A revised version of this paper was published in the "proceedings" volume for this conference: Conn, Stephen. (1991). "Punishment in Pre-Colonial Indigenous Societies in North America." La peine, Quatrième partie.
Conn, Stephen
core
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Original paper Pain associated with the musculoskeletal system in children from Warsaw schools
Objective : To assess the prevalence of pain in the musculoskeletal system and possible reasons for these complaints among early age children from Warsaw schools.
Iwona Słowińska +5 more
doaj +1 more source
Microseismic data shows that some unconventional reservoirs comprise well-developed natural fractures and complex hydraulic fracture networks. It is neither practical nor advantageous to simulate a huge number of natural and hydraulic fractures with ...
Zhiming Chen, Xinwei Liao, Wei Yu
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Original scientific paper optimization of ventilation using IIOT methodology in Serbian coal mines [PDF]
The application of information technologies in the optimization of ventilation contributes significantly to the improvement of all aspects of mine operations.
Ilić Aleksandra, Petrović Dejan
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Objectives : The presence of human leukocyte antigen B27 (HLA-B27) is strongly associated with ankylosing spondylitis. HLA-B27 testing is routinely applied in the diagnosis of this disease.
Urszula Skalska +3 more
doaj +1 more source

