Results 91 to 100 of about 58,042,140 (212)
Health Research Board annual report 2017 [PDF]
, 2018 Annual report for the HRB, which funds and performs research in ...
Health Research Board
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Health Research Board Strategy 2021–2025 [with summary]
, 2021 Over the next five years, we will deliver a strategic and well-balanced funding portfolio that responds to the needs of the population, the health and social care system, and the economy. This means balancing our support for research in targeted priority
Health Research Board
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The Original Newspaper Collection has a growing collection of newspaper titles. The majority of the newspapers date from the 19th and 20th centuries; however, a select few date back to the 18th century. Many of the newspapers were published in Baltimore,
Original Newspaper Collection
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Health research in action 2017
, 2017 Actions and outcomes enabled by HRB-funded ...
Health Research Board
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Overall view, side view; Hellenistic realism extended to the expressive portrayal of animals as well as humans. Many bronze animal sculptures of this period are only known to us through Roman marble copies.
unknown (Ancient Roman sculptor, after Greek original)
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source